Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central
nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis …

Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly
expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at …

Antibody-Mediated Encephalitis The category of autoimmune encephalitides constitutes
disorders with relatively distinct characteristics such as psychosis, seizures, abnormal …

Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing, autoimmune,
inflammatory disorder that typically affects the optic nerves and spinal cord. At least two …

Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that
primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of …

Background and Objective There are few studies comparing lesion evolution across different
CNS demyelinating diseases, yet knowledge of this may be important for diagnosis and …

Introduction Severe attacks of neuromyelitis optica spectrum disorder (NMO-SD) are
improved by plasma exchange (PLEX) given as an adjunctive therapy. Initial studies failed …

The understanding of neuromyelitis optica spectrum disorder (NMOSD) has evolved
substantially since its initial description over a century ago. The discovery in 2004 of a …

The aquaporins (AQPs) are a family of small, integral membrane proteins that facilitate water
transport across the plasma membranes of cells in response to osmotic gradients. Data from …