The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

Ferroptosis is a newly discovered form of regulated cell death dependent on iron and
reactive oxygen species (ROS). It directly or indirectly affects the activity of glutathione …

Rationale: Pyroptosis is a morphologically and mechanistically distinct form of cell death and
is characterized by GSDMD (gasdermin D) or GSDME (gasdermin E)-mediated necrosis …

Doxorubicin (DOX) is a powerful and commonly used chemotherapeutic drug, used alone or
in combination in a variety of cancers, while it has been found to cause serious cardiac side …

Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …

Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …

Objectives To identify the cooperation and impact of authors, countries, institutions, and
journals, evaluate the knowledge base, find the hotspot trends, and detect the emerging …

Arachidonic and adrenic acids in the membrane play key roles in ferroptosis. Here, we
reveal that lipoprotein-associated phospholipase A2 (Lp-PLA2) controls intracellular …

Objective Ferroptosis is indicated in cardiovascular diseases. Given the prominent role of
mitophagy in the governance of ferroptosis and our recent finding for FUN14 domain …