Bromination is one of the most important transformations in organic synthesis and can be
carried out using bromine and many other bromo compounds. Use of molecular bromine in …

Publisher Summary This chapter reviews developments in the field of isatin from 1944 to late
1974. The most frequently used synthesis of isatins is the Sandmeyer procedure, which …

The halogens, through themselves simple inorganic molecules, react with a wide range of
organic compounds, and in doing so provide new compounds in great variety and of …

The word indole is derived from the word India: indigo (3), the blue dye, was first exported
from India to Europe in the 16th century. Indoles are generally crystalline colorless solids …

Coupling reactions of indoles forming 2, 2'-biindolyls have been investigated. 2-Iodo-N-
methyl-indole and unactivated copper gave N, N'-dimethyl-2, 2'-biindolyl whereas activated …

A superior synthethic method for the bromination of indoles and benzimidazoles -ORCA
Cardiff University | Prifysgol Caerdydd ORCA Online Research @ Cardiff Cardiff University …

JP 2004-256443 9, 2004 WO 94f13637 A1 6, 1994 WO 94f14434 A1 T 1994 WO 94.26738
A1 11, 1994 WO 95/10513 A1 4f1995 WO 96, 06840 A1 3, 1996 WO 96/21656 A1 T 1996 …

Treatment of methyl indole-3-carboxylate with bromine in acetic acid gives methyl 5, 6-
dibromoindole-3-carboxylate regioselectively, from which the parent 5, 6-dibromoindole can …

A regioselective synthesis of N-carbomethoxy-2, 3, 5-tribromoindole (6) via a sequential one-
pot bromination− aromatization− bromination of N-carbomethoxyindoline (2) is described …

Dibromo-tryptophan is an interesting amino acid whose derivatives and analogues are
found in a variety of highly bioactive natural compounds. Notwithstanding its relevance no …