[HTML][HTML] The Use of Human Mesenchymal Stem Cells as Therapeutic Agents for the in vivo Treatment of Immune-Related Diseases: A Systematic Review

A Leyendecker Jr, CCG Pinheiro, MT Amano… - Frontiers in …, 2018 - frontiersin.org
Background: One of the greatest challenges for medicine is to find a safe and effective
treatment for immune-related diseases. However, due to the low efficacy of the treatment …

[HTML][HTML] Multipotent mesenchymal stromal cells in rheumatoid arthritis and systemic lupus erythematosus; from a leading role in pathogenesis to potential therapeutic …

JJ El-Jawhari, Y El-Sherbiny, D McGonagle… - Frontiers in …, 2021 - frontiersin.org
The pathogenesis of the autoimmune rheumatological diseases including rheumatoid
arthritis (RA) and systemic lupus erythematosus (SLE) is complex with the involvement of …

[HTML][HTML] Immunomodulatory effect of human umbilical cord mesenchymal stem cells on T lymphocytes in rheumatoid arthritis

D Ma, K Xu, G Zhang, Y Liu, J Gao, M Tian… - International …, 2019 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease which is lack of effective therapies.
Abnormal activation, proliferation, and differentiation of T lymphocytes are closely related to …

Cell‐based therapies for the treatment of rheumatoid arthritis

MZ Moghaddam, MJ Mousavi… - Immunity, Inflammation …, 2023 - Wiley Online Library
Autoimmune diseases, including rheumatoid arthritis that is the most prevalent rheumatic
autoimmune disorder, affect autologous connective tissues caused by the breakdown of the …

Long‐term passages of human clonal mesenchymal stromal cells can alleviate the disease in the rat model of collagen‐induced arthritis resembling early passages of …

M Babaahmadi, B Tayebi, NM Gholipour… - Journal of Tissue …, 2022 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease of unknown cause. The
interaction of immune system cells and the secretion of inflammatory cytokines with synovial …

[PDF][PDF] Anti-inflammatory and antioxidant effects of mesenchymal and hematopoietic stem cells in a rheumatoid arthritis rat model

H Abdelmawgoud, A Saleh - Adv Clin Exp Med, 2018 - dbc.wroc.pl
Abstract Background. Mesenchymal stem cells (MSCs) are of increased importance
because of their capacity to counteract inflammation and suppress host immune responses …

[HTML][HTML] Autologous bone marrow-derived mesenchymal stem cells modulate molecular markers of inflammation in dogs with cruciate ligament rupture

P Muir, EC Hans, M Racette, N Volstad, SJ Sample… - PLoS …, 2016 - journals.plos.org
Mid-substance rupture of the canine cranial cruciate ligament rupture (CR) and associated
stifle osteoarthritis (OA) is an important veterinary health problem. CR causes stifle joint …

[HTML][HTML] Induction of CD4+CD25+FOXP3+ regulatory T cells by mesenchymal stem cells is associated with modulation of ubiquitination factors and TSDR …

M Khosravi, A Bidmeshkipour, JL Cohen… - Stem Cell Research & …, 2018 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are known for their ability to induce
the conversion of conventional T cells (Tconvs) into induced regulatory T cells (iTregs) in …

[HTML][HTML] Mesenchymal stem cell-macrophage choreography supporting spinal cord repair

I Maldonado-Lasunción, J Verhaagen, M Oudega - Neurotherapeutics, 2018 - Elsevier
Spinal cord injury results in destructive events that lead to tissue loss and functional
impairments. A hallmark of spinal cord injury is the robust and persistent presence of …

Immunomodulatory benefits of mesenchymal stem cells treated with Caffeine in adjuvant-induced arthritis

EM Ghaffary, SMA Froushani - Life sciences, 2020 - Elsevier
Purpose We intend to assess the effect of the conditioned medium of Caffeine pulsed MSCS
in the amelioration of rheumatoid arthritis (RA)-afflicted rats. Methods MSCs were incubated …