[HTML][HTML] Engineering the multiscale complexity of vascular networks

C O'Connor, E Brady, Y Zheng, E Moore… - Nature Reviews …, 2022 - nature.com
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds

RJ Mondschein, A Kanitkar, CB Williams, SS Verbridge… - Biomaterials, 2017 - Elsevier
This review highlights the synthesis, properties, and advanced applications of synthetic and
natural polymers 3D printed using stereolithography for soft tissue engineering applications …

Multivascular networks and functional intravascular topologies within biocompatible hydrogels

B Grigoryan, SJ Paulsen, DC Corbett, DW Sazer… - Science, 2019 - science.org
Solid organs transport fluids through distinct vascular networks that are biophysically and
biochemically entangled, creating complex three-dimensional (3D) transport regimes that …

Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

X Ma, X Qu, W Zhu, YS Li, S Yuan… - Proceedings of the …, 2016 - National Acad Sciences
The functional maturation and preservation of hepatic cells derived from human induced
pluripotent stem cells (hiPSCs) are essential to personalized in vitro drug screening and …

A liver-on-a-chip platform with bioprinted hepatic spheroids

NS Bhise, V Manoharan, S Massa, A Tamayol… - …, 2016 - iopscience.iop.org
The inadequacy of animal models in correctly predicting drug and biothreat agent toxicity in
humans has resulted in a pressing need for in vitro models that can recreate the in vivo …

[HTML][HTML] 3D Bioprinted cancer models: Revolutionizing personalized cancer therapy

R Augustine, SN Kalva, R Ahmad, AA Zahid… - Translational …, 2021 - Elsevier
After cardiovascular disease, cancer is the leading cause of death worldwide with
devastating health and economic consequences, particularly in developing countries. Inter …

3D bioprinting of functional tissue models for personalized drug screening and in vitro disease modeling

X Ma, J Liu, W Zhu, M Tang, N Lawrence, C Yu… - Advanced drug delivery …, 2018 - Elsevier
Abstract 3D bioprinting is emerging as a promising technology for fabricating complex tissue
constructs with tailored biological components and mechanical properties. Recent advances …

25th anniversary article: Rational design and applications of hydrogels in regenerative medicine

N Annabi, A Tamayol, JA Uquillas, M Akbari… - Advanced …, 2014 - Wiley Online Library
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …

Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

N Huebsch, E Lippens, K Lee, M Mehta, ST Koshy… - Nature materials, 2015 - nature.com
The effectiveness of stem cell therapies has been hampered by cell death and limited
control over fate. These problems can be partially circumvented by using macroporous …

Spatiotemporal hydrogel biomaterials for regenerative medicine

TE Brown, KS Anseth - Chemical Society Reviews, 2017 - pubs.rsc.org
Hydrogels mimic many of the physical properties of soft tissue and are widely used
biomaterials for tissue engineering and regenerative medicine. Synthetic hydrogels have …