Design of three‐dimensional biomimetic scaffolds

SC Owen, MS Shoichet - Journal of biomedical materials …, 2010 - Wiley Online Library
A detailed understanding of the biophysical features that affect cell growth and development
is important in guiding the design of biomimetic scaffolds. The cellular microenvironment is a …

Heparin-based hydrogel as a matrix for encapsulation and cultivation of primary hepatocytes

M Kim, JY Lee, CN Jones, A Revzin, G Tae - Biomaterials, 2010 - Elsevier
Primary hepatocytes are commonly used as liver surrogates in toxicology and tissue
engineering fields, therefore, maintenance of functional hepatocytes in vitro is an important …

Biofabrication of Hepatic Constructs by 3D Bioprinting of a Cell‐Laden Thermogel: An Effective Tool to Assess Drug‐Induced Hepatotoxic Response

M Gori, SM Giannitelli, M Torre… - Advanced …, 2020 - Wiley Online Library
A thermoresponsive Pluronic/alginate semisynthetic hydrogel is used to bioprint 3D hepatic
constructs, with the aim to investigate liver‐specific metabolic activity of the 3D constructs …

Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues

W Bian, B Liau, N Badie, N Bursac - Nature protocols, 2009 - nature.com
This protocol describes a cell/hydrogel molding method for precise and reproducible
biomimetic fabrication of three-dimensional (3D) muscle tissue architectures in vitro. Using a …

Microfluidic hydrogels for tissue engineering

GY Huang, LH Zhou, QC Zhang, YM Chen, W Sun… - …, 2011 - iopscience.iop.org
With advanced properties similar to the native extracellular matrix, hydrogels have found
widespread applications in tissue engineering. Hydrogel-based cellular constructs have …

Advances in precision microfabrication through digital light processing: system development, material and applications

X Wang, J Liu, Y Zhang, PM Kristiansen… - Virtual and Physical …, 2023 - Taylor & Francis
ABSTRACT Digital Light Processing (DLP) is an advanced additive manufacturing
technology which has garnered substantial recognition and has been extensively …

The promotion of microvasculature formation in poly (ethylene glycol) diacrylate hydrogels by an immobilized VEGF-mimetic peptide

JE Leslie-Barbick, JE Saik, DJ Gould, ME Dickinson… - Biomaterials, 2011 - Elsevier
Microvascularization of tissue engineered constructs was achieved by utilizing a VEGF-
mimicking peptide, QK, covalently bound to a poly (ethylene glycol) hydrogel matrix. The 15 …

Concave microwell based size-controllable hepatosphere as a three-dimensional liver tissue model

SF Wong, YY Choi, DS Kim, BG Chung, SH Lee - Biomaterials, 2011 - Elsevier
We have developed a size-controllable spheroidal hepatosphere and heterosphere model
by mono-culturing of primary hepatocytes and by co-culturing primary hepatocytes and …

Photo-cross-linkable methacrylated gelatin and hydroxyapatite hybrid hydrogel for modularly engineering biomimetic osteon

Y Zuo, X Liu, D Wei, J Sun, W Xiao… - … applied materials & …, 2015 - ACS Publications
Modular tissue engineering holds great potential in regenerating natural complex tissues by
engineering three-dimensional modular scaffolds with predefined geometry and biological …

Digital manufacturing for microfluidics

A Naderi, N Bhattacharjee… - Annual review of …, 2019 - annualreviews.org
The microfluidics field is at a critical crossroads. The vast majority of microfluidic devices are
presently manufactured using micromolding processes that work very well for a reduced set …