Methods This systematic review aims to investigate the effects of ketamine in OCD, following
the Preferred Reporting Items for Systematic Review and Meta-analyses Protocols (PRISMA …

Post-traumatic stress disorder (PTSD) is an anxiety disorder with manifestations somatic
resulting from reliving the trauma. The therapy for the treatment of PTSD has limitations …

Abstract Background At-home Ketamine-assisted therapy (KAT) with psychosocial support
and remote monitoring through telehealth platforms addresses access barriers, including the …

Background In this post-hoc analysis, data from 2 positive, pivotal, phase 3 trials of
esketamine nasal spray (ESK) in treatment-resistant depression (TRD)—short-term study …

There are significantly fewer options for the treatment of bipolar depression than major
depressive disorder, with an urgent need for alternative therapies. In this pilot study, we …

Rationale The relationship between subjective drug experience and antidepressant
outcomes for ketamine derivatives is poorly understood but of high clinical relevance …

Abstract Approximately 10%–30% of individuals with posttraumatic stress disorder (PTSD)
exhibit a dissociative subtype of the condition defined by symptoms of depersonalization …

There is evidence for ketamine use in treatment-resistant depression (TRD). Several safety
and tolerability concerns arise regarding adverse drug reactions and specific …

This study is the first randomized controlled trial to test the effects of ketamine in Borderline
Personality Disorder (BPD). BPD remains undertreated in the community and no medication …

Rationale A significant obstacle to an improved understanding of pathological dissociative
and psychosis-like states is the lack of readily implemented pharmacological models of …