Thiophenes—naturally occurring plant metabolites: Biological activities and in silico evaluation of their potential as cathepsin D inhibitors
SRM Ibrahim, AM Omar, AA Bagalagel, RM Diri… - Plants, 2022 - mdpi.com
Naturally, thiophenes represent a small family of natural metabolites featured by one to five
thiophene rings. Numerous plant species belonging to the family Asteraceae commonly …
thiophene rings. Numerous plant species belonging to the family Asteraceae commonly …
Therapeutic potential of thiophene compounds: a mini-review
S Chawla, S Sharma, S Kashid… - Mini Reviews in …, 2023 - ingentaconnect.com
A rising number of researchers are interested in thiophene-based analogs as they have
wide possibilities of biological potential in the largely developing chemical world of the …
wide possibilities of biological potential in the largely developing chemical world of the …
Synthesis, and docking studies of novel heterocycles incorporating the indazolylthiazole moiety as antimicrobial and anticancer agents
NTA Dawoud, EM El-Fakharany, AE Abdallah… - Scientific Reports, 2022 - nature.com
The current study was directed toward developing a new series of fused heterocycles
incorporating indazolylthiazole moiety. The newly synthesized compounds were …
incorporating indazolylthiazole moiety. The newly synthesized compounds were …
Synthesis, characterization, computational assay and anti-inflammatory activity of thiosemicarbazone derivatives: Highly potent and efficacious for COX inhibitors
K Saeed, M Rafiq, M Khalid, A Hussain… - International …, 2024 - Elsevier
Multiple studies in the literature have demonstrated that synthetic compounds containing
heterocyclic rings possess a reparative potential against acute and chronic inflammation. In …
heterocyclic rings possess a reparative potential against acute and chronic inflammation. In …
New naphtho/thienobenzo-triazoles with interconnected anti-inflammatory and cholinesterase inhibitory activity
Abstract New 1, 2, 3-triazolo (thieno) stilbenes were synthesized by Wittig reaction and
photochemically transformed to corresponding substituted thienobenzo/naphtho-triazoles in …
photochemically transformed to corresponding substituted thienobenzo/naphtho-triazoles in …
3‐Amino‐thiophene‐2‐carbohydrazide derivatives as anti Colon cancer Agents: synthesis, characterization, in‐Silico and in‐Vitro Biological activity studies
In this study, starting from 3‐amino‐thiophene‐2‐carboxylic acid methyl ester, eighteen new
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …
Synthesis, molecular modeling, and anticancer activity of new thiophene and thiophene-pyrazole analogues incorporating benzene-sulfonamide moiety as carbonic …
AI Alalawy, K Alatawi, NA Alenazi, AF Qarah… - Journal of Molecular …, 2024 - Elsevier
Two series of new substituted thiophene and their corresponding thiophene-pyrazole
analogues-based benzene-sulfonamide were synthesized and characterized by various …
analogues-based benzene-sulfonamide were synthesized and characterized by various …
CuO nanoparticles for green synthesis of significant anti-Helicobacter pylori compounds with in silico studies
WS Shehab, DA Elsayed, AM Abdel Hamid… - Scientific Reports, 2024 - nature.com
Helicobacter pylori (H. pylori) is a universal health intimidation as mentioned by the World
Health Organization. The primary causal agent linked to a number of illnesses, including …
Health Organization. The primary causal agent linked to a number of illnesses, including …
The Ethnopharmacological Uses, Metabolite Diversity, and Bioactivity of Rhaponticum uniflorum (Leuzea uniflora): A Comprehensive Review
DN Olennikov - Biomolecules, 2022 - mdpi.com
Rhaponticum uniflorum (L.) DC.(syn. Leuzea uniflora (L.) Holub) is a plant species of the
Compositae (Asteraceae) family that is widely used in Asian traditional medicines in China …
Compositae (Asteraceae) family that is widely used in Asian traditional medicines in China …
Design, synthesis, anti-inflammatory evaluation and molecular docking of novel thiophen-2-ylmethylene-based derivatives as potential TNF-α production inhibitors
DH Dawood, ES Nossier, MF Abdelhameed… - Bioorganic …, 2022 - Elsevier
Inflammation is considered to be an alarming signal for the progress of varied biological
complications. Based on the previous reports in the literature that proved the noticeable …
complications. Based on the previous reports in the literature that proved the noticeable …