A 35-year-old man presents with a febrile illness after travel in West Africa, and severe
malaria is diagnosed. Treatment with artesunate is recommended. Artesunate is a member …

Antimalarial drugs have played a mainstream role in controlling the spread of malaria
through the treatment of patients infected with the plasmodial parasites and controlling its …

Abstract Multicenter trials in Southeast Asia have shown better survival rates among patients
with severe malaria, particularly those with high parasitemia levels, treated with intravenous …

Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a deadly
complication of malaria, and its pathophysiology is insufficiently understood. Both in humans …

The artemisinins are the most effective antimalarial drugs known. They possess a
remarkably wide therapeutic index. These agents have been used in traditional Chinese …

The clinical manifestations of cerebral malaria (CM) are well correlated with underlying
major pathophysiological events occurring during an acute malaria infection, the most …

Replenishment of arginine and restoration of nitric oxide production in clinical malaria
should diminish parasitized red blood cells adherence to endothelium and reduce the …

In vitro propagated Artemisia annua plantlets were exposed to low dose (2.8 W m− 2) of UV-
B (280–315 nm) radiation for different short-term (1, 2, 3 and 4 h) durations that resulted in …

Abstract Background: The Lives Saved Tool (LiST) model was developed to estimate the
impact of the scale-up of child survival interventions on child mortality. New advances in …

Introduction Severe malaria is a life-threatening medical emergency and requires prompt
and effective treatment to prevent death. There is paucity of published information on current …