Mother-to-child-transmission rates of HIV in the absence of any intervention range between
20 and 45%. However, the provision of antiretroviral drugs (ARVs) during pregnancy …

The concept of 'standby emergency treatment'(SBET) describes the strategy where travelers
carry an emergency malaria treatment for self-administration when no medical attention is …

Background: More than 90% of pregnant women take at least one drug during pregnancy.
Drug dose adjustments during pregnancy are sometimes necessary due to various …

The present review aimed to synthesise available evidence on the efficacy of
dihydroartemisinin-piperaquine (DP) in treating uncomplicated Plasmodium falciparum …

Background This study aimed to synthesize available evidence on the efficacy of
dihydroartemisinin-piperaquine (DHP) in treating uncomplicated Plasmodium vivax malaria …

Background Pregnancy has been reported to alter the pharmacokinetic properties of anti-
malarial drugs, including the different components of artemisinin-based combination therapy …

Orally administered artemisinin-based combination therapy is the first-line treatment against
uncomplicated P. falciparum malaria worldwide. However, the increasing prevalence of …

Malaria remains a global public health concern and current treatment options are
suboptimal in some clinical settings. For effective chemotherapy, antimalarial drug …

Introduction The association between pregnancy and altered drug pharmacokinetic (PK)
properties is acknowledged, as is its impact on drug plasma concentrations and thus …

Background Currently, population pharmacokinetic (PK) studies of anti-malarial drugs are
designed primarily by the logistical and ethical constraints of taking blood samples from …