[HTML][HTML] Role of extracellular vesicles (EVs) in cell stress response and resistance to cancer therapy

CP O'Neill, KE Gilligan, RM Dwyer - Cancers, 2019 - mdpi.com
Extracellular vesicles (EVs) are nanosized particles released by all cells that have been
heralded as novel regulators of cell-to-cell communication. It is becoming increasingly clear …

Reactive oxygen species (ROS): Critical roles in breast tumor microenvironment

RR Malla, N Surepalli, B Farran, SV Malhotra… - Critical Reviews in …, 2021 - Elsevier
Increases in Reactive oxygen species (ROS) have been reported in breast tumors and their
surrounding tumor microenvironment (TME) cells. ROS are critical factors in breast TME as …

Potential phytocompounds for developing breast cancer therapeutics: nature's healing touch

J Iqbal, BA Abbasi, R Batool, T Mahmood, B Ali… - European Journal of …, 2018 - Elsevier
Breast cancer (BC) is a devastating disease in female around the world causing significant
health care burden in both developed and developing countries. In many cases BC has …

The Natural Products and Extracts: Anti‐Triple‐Negative Breast Cancer in Vitro

H Chen, J Yang, Y Yang, J Zhang, Y Xu… - Chemistry & …, 2021 - Wiley Online Library
Triple‐negative breast cancer (TNBC) makes up 15% to 20% of all breast cancer (BC)
cases, and represents one of the most challenging malignancies to treat. For many years …

[HTML][HTML] Redox-dependent thiol modifications: implications for the release of extracellular vesicles

BJ Benedikter, AR Weseler, EFM Wouters… - Cellular and molecular …, 2018 - Springer
Extracellular vesicles (EVs), including microvesicles and exosomes, are emerging as
important regulators of homeostasis and pathophysiology. During pro-inflammatory and pro …

[HTML][HTML] Deoxyelephantopin induces apoptosis and enhances chemosensitivity of colon cancer via miR-205/bcl2 Axis

H Ji, K Zhang, G Pan, C Li, C Li, X Hu, L Yang… - International Journal of …, 2022 - mdpi.com
Colon cancer (CC) is one of the major causes of cancer death in humans. Despite recent
advances in the management of CC, the prognosis is still poor and a new strategy for …

[HTML][HTML] Mitophagy-related gene signature for prediction prognosis, immune scenery, mutation, and chemotherapy response in pancreatic cancer

Z Zhuo, H Lin, J Liang, P Ma, J Li, L Huang… - Frontiers in Cell and …, 2022 - frontiersin.org
Mitophagy is a conserved cellular process that plays a vital role in maintaining cellular
homeostasis by selectively removing dysfunctional mitochondria. Notwithstanding that …

[HTML][HTML] Treating Cancer through Modulating Exosomal Protein Loading and Function: The Prospects of Natural Products and Traditional Chinese Medicine

L Meng, C Zhang, P Yu - Pharmacological Research, 2024 - Elsevier
Exosomes, small yet vital extracellular vesicles, play an integral role in intercellular
communication. They transport critical components, such as proteins, lipid bilayers, DNA …

[HTML][HTML] Extracellular vesicles: the landscape in the progression, diagnosis, and treatment of triple-negative breast cancer

M Dong, Q Liu, Y Xu, Q Zhang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer (BC) with
diverse biological behavior, high aggressiveness, and poor prognosis. Extracellular vesicles …

[HTML][HTML] Deregulating the CYP2C19/epoxy-eicosatrienoic acid-associated FABP4/FABP5 signaling network as a therapeutic approach for metastatic triple-negative …

MK Apaya, PW Hsiao, YC Yang, LF Shyur - Cancers, 2020 - mdpi.com
Recurrence and metastasis are the main causes of triple-negative breast cancer (TNBC)
mortality. On the basis of our clinical cohorts and integrative omics analyses, we …