[HTML][HTML] Neutrophils as drivers of immune dysregulation in autoimmune diseases with skin manifestations

S Nakabo, J Romo-Tena, MJ Kaplan - Journal of Investigative Dermatology, 2022 - Elsevier
Dysregulation in the phenotype and function of neutrophils may play important roles in the
initiation and perpetuation of autoimmune responses, including conditions affecting the skin …

Adsorptive granulocyte and monocyte apheresis for refractory Crohn's disease: an open multicenter prospective study

Y Fukuda, T Matsui, Y Suzuki, K Kanke… - Journal of …, 2004 - Springer
Abstract Background Active Crohn's disease (CD) is often associated with elevated levels of
platelets, granulocytes, and monocytes that are activated and resistant to apoptosis. The …

Granulocytapheresis is useful as an alternative therapy in patients with steroid-refractory or-dependent ulcerative colitis

M Naganuma, S Funakoshi, A Sakuraba… - Inflammatory bowel …, 2004 - academic.oup.com
Background Recently, granulocyte and monocyte adsorption apheresis (GCAP) has been
shown to be safe and effective for active ulcerative colitis (UC). We analyzed the safety and …

A role for granulocyte and monocyte apheresis in the treatment of rheumatoid arthritis

N Kashiwagi, I Hirata, R Kasukawa - Therapeutic Apheresis, 1998 - Wiley Online Library
Rheumatoid arthritis (RA) is an inflammatory condition, the etiology of which is not well
understood. Recent reports indicate a major role of granulocytes in the pathogenesis of RA; …

Clinical evaluation of granulocyte/monocyte apheresis therapy for active ulcerative colitis

K Kanke, M Nakano, H Hiraishi, A Terano - Digestive and liver disease, 2004 - Elsevier
BACKGROUND.: Recent evidence suggests that peripheral blood granulocytes and
monocytes/macrophages have a major role in the exacerbation of ulcerative colitis. AIMS …

Granulocytapheresis for Crohn's disease: a report on seven refractory patients

T Matsui, T Nishimura, H Matake, T Ohta… - Official journal of the …, 2003 - journals.lww.com
TO THE EDITOR: Active Crohn's disease (CD) is often associated with elevated and
activated monocytes/macrophages and granulocytes (1–3), which are major sources of …

Therapeutic efficacy of granulocyte and monocyte adsorption apheresis in severe active ulcerative colitis

H Hanai, F Watanabe, AR Saniabadi… - Digestive diseases …, 2002 - search.proquest.com
Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease that appears
with varying severity. The disease is associated with activation of the immune system and …

Adhesion dependent release of hepatocyte growth factor and interleukin-1 receptor antagonist from human blood granulocytes and monocytes: evidence for the …

Y Takeda, N Shiobara, AR Saniabadi, M Adachi… - Inflammation …, 2004 - Springer
Objective: Evolving evidence of anti-inflammatory effects is observed in patients with
rheumatoid arthritis or ulcerative colitis following periodic adsorptive granulocyte and …

A retrospective search for predictors of clinical response to selective granulocyte and monocyte apheresis in patients with ulcerative colitis

Y Suzuki, N Yoshimura, K Fukuda, K Shirai… - Digestive diseases and …, 2006 - Springer
Recently, selective granulocytapheresis (Adacolumn) has appeared as a new treatment for
patients with inflammatory bowel disease. This study sought to determine predictors of …

Granulocyte adsorptive apheresis for pediatric patients with ulcerative colitis

T Tomomasa, A Kobayashi, H Kaneko, S Mika… - Digestive diseases and …, 2003 - Springer
Granulocytapheresis (GCAP) has produced efficacy in adult patients with ulcerative colitis
(UC) by adsorbing activated granulocytes and monocytes/macrophages. We retrospectively …