Colorectal cancer development and advances in screening

K Simon - Clinical interventions in aging, 2016 - Taylor & Francis
Most colon tumors develop via a multistep process involving a series of histological,
morphological, and genetic changes that accumulate over time. This has allowed for …

Emerging trends in colorectal cancer: Dysregulated signaling pathways

R Ahmad, JK Singh, A Wunnava… - International …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …

British Society of Gastroenterology position statement on serrated polyps in the colon and rectum

JE East, WS Atkin, AC Bateman, SK Clark, S Dolwani… - Gut, 2017 - gut.bmj.com
Serrated polyps have been recognised in the last decade as important premalignant lesions
accounting for between 15% and 30% of colorectal cancers. There is therefore a clinical …

Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening (SCREESCO): preliminary report of a …

A Forsberg, M Westerberg, C Metcalfe… - The lancet …, 2022 - thelancet.com
Background Screening for colorectal cancer is done with lower gastrointestinal endoscopy
or stool-based tests. There is little evidence from randomised trials to show primary …

Advanced endoscopic imaging: European Society of Gastrointestinal Endoscopy (ESGE) technology review

JE East, JL Vleugels, P Roelandt, P Bhandari… - …, 2016 - thieme-connect.com
Background and aim: This technical review is an official statement of the European Society
of Gastrointestinal Endoscopy (ESGE). It addresses the utilization of advanced endoscopic …

Narrow band imaging optical diagnosis of small colorectal polyps in routine clinical practice: the Detect Inspect Characterise Resect and Discard 2 (DISCARD 2) study

CJ Rees, PT Rajasekhar, A Wilson, H Close, MD Rutter… - Gut, 2017 - gut.bmj.com
Background Accurate optical characterisation and removal of small adenomas (< 10 mm) at
colonoscopy would allow hyperplastic polyps to be left in situ and surveillance intervals to …

Narrow-band imaging for detection of neoplasia at colonoscopy: a meta-analysis of data from individual patients in randomized controlled trials

NSS Atkinson, S Ket, P Bassett, D Aponte, S De Aguiar… - Gastroenterology, 2019 - Elsevier
Background & Aims Adenoma detection rate (ADR) is an important quality assurance
measure for colonoscopy. Some studies suggest that narrow-band imaging (NBI) may be …

Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised …

MA Hull, K Sprange, T Hepburn, W Tan, A Shafayat… - The Lancet, 2018 - thelancet.com
Background The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) and
aspirin both have proof of concept for colorectal cancer chemoprevention, aligned with an …

Endoscopic diagnosis and treatment planning for colorectal polyps using a deep-learning model

EM Song, B Park, CA Ha, SW Hwang, SH Park… - Scientific reports, 2020 - nature.com
We aimed to develop a computer-aided diagnostic system (CAD) for predicting colorectal
polyp histology using deep-learning technology and to validate its performance. Near-focus …

Cold EMR of large sessile serrated polyps at colonoscopy (with video)

NJ Tutticci, DG Hewett - Gastrointestinal endoscopy, 2018 - Elsevier
Background and Aims The optimal technique for the resection of sessile serrated polyps
(SSPs) is unknown, with established limitations and risks with conventional polypectomy …