[HTML][HTML] Laboratory testing in patients treated with direct oral anticoagulants: a practical guide for clinicians

J Douxfils, W Ageno, CM Samama, S Lessire… - Journal of Thrombosis …, 2018 - Elsevier
Click to hear Dr Baglin's perspective on the role of the laboratory in treatment with new oral
anticoagulants Summary One of the key benefits of the direct oral anticoagulants (DOACs) is …

[HTML][HTML] Testing and monitoring direct oral anticoagulants

JM Connors - Blood, 2018 - Elsevier
Direct oral anticoagulants (DOACs) have significantly improved the care of patients requiring
anticoagulation. With similar or better efficacy and safety outcomes and easier use in the …

International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of direct oral anticoagulants

RC Gosselin, DM Adcock, SM Bates… - Thrombosis and …, 2018 - thieme-connect.com
This guidance document was prepared on behalf of the International Council for
Standardization in Haematology (ICSH) for providing haemostasis-related guidance …

2021 update of the International Council for Standardization in Haematology recommendations for laboratory measurement of direct oral anticoagulants

J Douxfils, DM Adcock, SM Bates… - Thrombosis and …, 2021 - thieme-connect.com
In 2018, the International Council for Standardization in Haematology (ICSH) published a
consensus document providing guidance for laboratories on measuring direct oral …

Direct oral anticoagulant monitoring: what laboratory tests are available to guide us?

R Sarode - Hematology 2014, the American Society of …, 2019 - ashpublications.org
Direct oral anticoagulants (DOACs) are increasingly used in the treatment and prophylaxis
of thromboembolism because of several advantages over vitamin K antagonists, including …

Anti-Xa oral anticoagulant plasma concentration assay in real life: rivaroxaban and apixaban quantification in emergency with LMWH calibrator

P Billoir, V Barbay, LM Joly, M Fresel… - Annals of …, 2019 - journals.sagepub.com
Background: Oral anti-Xa inhibitors have demonstrated noninferiority to vitamin K
antagonists (VKAs) for the prevention of stroke in patients with atrial fibrillation and recurrent …

[HTML][HTML] Accuracy of a single, heparin-calibrated anti-Xa assay for the measurement of rivaroxaban, apixaban, and edoxaban drug concentrations: a prospective cross …

T Meihandoest, JD Studt, A Mendez… - Frontiers in …, 2022 - frontiersin.org
Background Applying a single anti-Xa assay, calibrated to unfractionated heparin to
measure rivaroxaban, apixaban, and edoxaban would simplify laboratory procedures and …

[HTML][HTML] Rivaroxaban and apixaban are less effective than enoxaparin for the prevention of catheter-induced clotting in vitro

Z Guan, R Wang, RH Hussain, JC Fredenburgh… - Journal of Thrombosis …, 2023 - Elsevier
Background Central venous catheters are prone to clotting, particularly in patients with
cancer. Although low-molecular-weight heparin and direct oral anticoagulants, such as …

[HTML][HTML] The myths behind DOAC measurement: Analyses of prescribing information from different regulatory bodies and a call for harmonization

RC Gosselin, EJ Favaloro, J Douxfils - Journal of Thrombosis and …, 2022 - Elsevier
For more than a decade, US laboratories have failed to implement solutions to help their
clinicians in managing complex situations or patients on direct oral anticoagulants (DOACs) …

Overview and practical application of coagulation assays in managing anticoagulation with direct oral anticoagulants (DOACs)

J Rimsans, J Douxfils, MA Smythe… - Current Pharmacology …, 2020 - Springer
Abstract Purpose of Review The introduction of newer anticoagulants requires clinicians to
fully appreciate, interpret, and correctly apply the use of coagulation assays, such as the …