Diffuse Pleural Mesothelioma: Advances in Molecular Pathogenesis, Diagnosis, and Treatment
CA Febres-Aldana, R Fanaroff, M Offin… - Annual Review of …, 2024 - annualreviews.org
Diffuse pleural mesothelioma (DPM) is a highly aggressive malignant neoplasm arising from
the mesothelial cells lining the pleural surfaces. While DPM is a well-recognized disease …
the mesothelial cells lining the pleural surfaces. While DPM is a well-recognized disease …
Pleural mesothelioma (PMe): The evolving molecular knowledge of a rare and aggressive cancer
M Rigon, L Mutti, M Campanella - Molecular Oncology, 2024 - Wiley Online Library
Mesothelioma is a type of late‐onset cancer that develops in cells covering the outer surface
of organs. Although it can affect the peritoneum, heart, or testicles, it mainly targets the lining …
of organs. Although it can affect the peritoneum, heart, or testicles, it mainly targets the lining …
Spatially resolved, high-dimensional transcriptomics sorts out the evolution of biphasic malignant pleural mesothelioma: new paradigms for immunotherapy
F Torricelli, B Donati, F Reggiani, V Manicardi, S Piana… - Molecular Cancer, 2023 - Springer
Abstract Background Malignant Pleural Mesothelioma (MPM) is a dreadful disease escaping
the classical genetic model of cancer evolution and characterized by wide heterogeneity …
the classical genetic model of cancer evolution and characterized by wide heterogeneity …
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo
M Benvenuto, V Angiolini, C Focaccetti, D Nardozi… - Biology Direct, 2023 - Springer
Background Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis. The low
efficacy of current treatment options highlights the urge to identify more effective therapies …
efficacy of current treatment options highlights the urge to identify more effective therapies …
The STING agonist, DMXAA, reduces tumor vessels and enhances mesothelioma tumor antigen presentation yet blunts cytotoxic T cell function in a murine model
PT Graham, AK Nowak, SMJ Cornwall, I Larma… - Frontiers in …, 2022 - frontiersin.org
We assessed the murine Stimulator of Interferon Genes (STING) agonist, DMXAA, for anti-
mesothelioma potential using the AE17-sOVA model that expresses ovalbumin (OVA) as a …
mesothelioma potential using the AE17-sOVA model that expresses ovalbumin (OVA) as a …
Malignant mesothelioma tumours: molecular pathogenesis, diagnosis, and therapies accompanying clinical studies
The pathetic malignant mesothelioma (MM) is a extremely uncommon and confrontational
tumor that evolves in the mesothelium layer of the pleural cavities (inner lining-visceral …
tumor that evolves in the mesothelium layer of the pleural cavities (inner lining-visceral …
A drug screening revealed novel potential agents against malignant pleural mesothelioma
I Dell'Anno, A Melani, SA Martin, M Barbarino… - Cancers, 2022 - mdpi.com
Simple Summary Malignant pleural mesothelioma (MPM) is a disease of the pleura related
to asbestos exposure. Despite the advancements in new therapeutic frontiers, it has a …
to asbestos exposure. Despite the advancements in new therapeutic frontiers, it has a …
ATG5 as biomarker for early detection of malignant mesothelioma
M Tomasetti, F Monaco, O Strogovets, L Volpini… - BMC Research …, 2023 - Springer
Objectives Malignant pleural mesothelioma (MPM) is an aggressive disease with grim
prognosis due to lack of effective treatment options. Disease prediction in association with …
prognosis due to lack of effective treatment options. Disease prediction in association with …
Targeting FAcilitates Chromatin Transcription complex inhibits pleural mesothelioma and enhances immunotherapy
Background Diffuse pleural mesothelioma (DPM) is an aggressive therapy-resistant cancer
with unique molecular features. Numerous agents have been tested, but clinically effective …
with unique molecular features. Numerous agents have been tested, but clinically effective …
The evolving role of immune-checkpoint inhibitors in Malignant pleural mesothelioma
M Borgeaud, F Kim, A Friedlaender, F Lococo… - Journal of Clinical …, 2023 - mdpi.com
Malignant pleural mesothelioma (MPM) is a rare cancer usually caused by asbestos
exposure and associated with a very poor prognosis. After more than a decade without new …
exposure and associated with a very poor prognosis. After more than a decade without new …