Abstract Structure‐based ligand design in medicinal chemistry and crop protection relies on
the identification and quantification of weak noncovalent interactions and understanding the …

More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …

Historically, emerging viruses appear constantly and have cost millions of human lives.
Currently, climate change and intense globalization have created favorable conditions for …

HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

HIV attacks the body's immune cells, frequently compromises the integrity of the blood–brain
barrier (BBB), and infects the CNS in the early stages of infection. Dysfunction of the BBB …

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …

The extent, regulation and enzymatic basis of RNA editing by cytidine deamination are
incompletely understood. Here we show that transcripts of hundreds of genes undergo site …

Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which
encompasses all spheres of science including chemistry, material science, biology, and …

Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …

Over the past several decades, extensive research into the Gag polyprotein, the main
structural protein of HIV-1 and all other retroviruses, has changed the way that we describe …