Advances in critical care for the nephrologist: acute lung injury/ARDS
KD Liu, MA Matthay - Clinical Journal of the American Society of …, 2008 - journals.lww.com
Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) are a major
cause of acute respiratory failure in the critically ill patient. ALI and ARDS are characterized …
cause of acute respiratory failure in the critically ill patient. ALI and ARDS are characterized …
[HTML][HTML] Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial
Background In a previous randomised controlled phase 2 trial, intravenous infusion of
salbutamol for up to 7 days in patients with acute respiratory distress syndrome (ARDS) …
salbutamol for up to 7 days in patients with acute respiratory distress syndrome (ARDS) …
[HTML][HTML] Pharmacological management of COVID-19 patients with ARDS (CARDS): a narrative review
MG Matera, P Rogliani, L Calzetta, M Cazzola - Respiratory medicine, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is highly infectious. It has been highlighted
that if not expertly and individually managed with consideration of the vasocentric features, a …
that if not expertly and individually managed with consideration of the vasocentric features, a …
The β-Agonist Lung Injury Trial (BALTI) a randomized placebo-controlled clinical trial
GD Perkins, DF McAuley, DR Thickett… - American journal of …, 2006 - atsjournals.org
Rationale: Experimental data suggest that manipulation of alveolar fluid clearance with β-
agonists can accelerate the resolution of alveolar edema and improve survival. Objective: To …
agonists can accelerate the resolution of alveolar edema and improve survival. Objective: To …
[HTML][HTML] Anti-inflammatory effects of β2 adrenergic receptor agonists in experimental acute lung injury
M Bosmann, JJ Grailer, K Zhu, MA Matthay… - The FASEB …, 2012 - ncbi.nlm.nih.gov
These studies were undertaken to extend emerging evidence that β 2 adrenergic receptor (β
2 AR) agonists, in addition to their bronchorelaxing effects, may have broad anti …
2 AR) agonists, in addition to their bronchorelaxing effects, may have broad anti …
The beta agonist lung injury trial prevention. A randomized controlled trial
Rationale: Experimental studies suggest that pretreatment with β-agonists might prevent
acute lung injury (ALI). Objectives: To determine if in adult patients undergoing elective …
acute lung injury (ALI). Objectives: To determine if in adult patients undergoing elective …
In vivo and in vitro effects of salbutamol on alveolar epithelial repair in acute lung injury
Background: Acute lung injury is an important cause of respiratory failure in the critically ill
patient. It is caused by damage to the alveolar barrier with subsequent alveolar flooding …
patient. It is caused by damage to the alveolar barrier with subsequent alveolar flooding …
Treatment of acute lung injury: current and emerging pharmacological therapies
R Mac Sweeney, M Griffiths… - Seminars in respiratory …, 2013 - thieme-connect.com
As a syndrome of injurious pulmonary inflammation resulting in deranged respiratory
physiology, acute lung injury affords numerous potential therapeutic targets. Two main …
physiology, acute lung injury affords numerous potential therapeutic targets. Two main …
[HTML][HTML] Treatments for pulmonary ricin intoxication: current aspects and future prospects
Y Gal, O Mazor, R Falach, A Sapoznikov, C Kronman… - Toxins, 2017 - mdpi.com
Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor beans),
is one of the most lethal toxins known, particularly if inhaled. Ricin is considered a potential …
is one of the most lethal toxins known, particularly if inhaled. Ricin is considered a potential …
Inhaled β2 adrenergic agonists and other cAMP-elevating agents: therapeutics for alveolar injury and acute respiratory disease syndrome?
K Sriram, MB Insel, PA Insel - Pharmacological Reviews, 2021 - ASPET
Inhaled long-acting β-adrenergic agonists (LABAs) and short-acting β-adrenergic agonists
are approved for the treatment of obstructive lung disease via actions mediated by β 2 …
are approved for the treatment of obstructive lung disease via actions mediated by β 2 …