[HTML][HTML] Past, present and future—β2-adrenoceptor agonists in asthma management
The β-adrenoceptor agonists (β-agonists) have been used to relieve bronchoconstriction for
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …
The β2-agonist controversy: observations, explanations and relationship to asthma epidemiology
MR Sears, DR Taylor - Drug Safety, 1994 - Springer
Links between frequent use of inhaled β2-agonists and morbidity and mortality from asthma
appear probable. Two mortality epidemics followed the marketing of potent inhaled …
appear probable. Two mortality epidemics followed the marketing of potent inhaled …
Regular inhaled beta-agonist treatment in bronchial asthma
MR Sears, DR Taylor, CG Print, DC Lake, Q Li… - The Lancet, 1990 - Elsevier
Abstract 89 subjects with stable asthma took part in a double-blind, placebo-controlled,
randomised, crossover study of the effects of regular versus on-demand inhaled …
randomised, crossover study of the effects of regular versus on-demand inhaled …
Comparison of regularly scheduled with as-needed use of albuterol in mild asthma
Background Inhaled β-agonists are the most commonly used treatment for asthma, but data
suggest that regularly scheduled use of these agents may have a deleterious effect on the …
suggest that regularly scheduled use of these agents may have a deleterious effect on the …
[图书][B] Innovation in the pharmaceutical industry: the process of drug discovery and development
T Hara - 2003 - books.google.com
" Addressing a number of practical implications for the promotion of the pharmaceutical
industry, this book will be of enormous interest to students, researchers and academics …
industry, this book will be of enormous interest to students, researchers and academics …
Albuterol: an adrenergic agent for use in the treatment of asthma pharmacology, pharmacokinetics and clinical use
RC Ahrens, GD Smith - Pharmacotherapy: The Journal of …, 1984 - Wiley Online Library
Albuterol is a long‐acting beta2‐adrenergic receptor‐selective drug that relaxes airway
smooth muscle. It is currently available in the United States in oral and metered‐dose …
smooth muscle. It is currently available in the United States in oral and metered‐dose …
The beta-agonist controversy
DR Taylor, MR Sears, DW Cockcroft - Medical Clinics, 1996 - medical.theclinics.com
BACKGROUND Despite widespread use of adrenergic agents in the management of
asthma for many decades, doubts have emerged concerning the safety and efficacy of long …
asthma for many decades, doubts have emerged concerning the safety and efficacy of long …
Inhaled short acting beta2‐agonist use in chronic asthma: regular versus as needed treatment
EH Walters, JAE Walters, PG Gibson… - Cochrane Database …, 1996 - cochranelibrary.com
Background Inhaled short‐acting beta‐2 agonists are the major class of bronchodilators
used for relief of symptoms in asthma. There has been concern that excessive uncontrolled …
used for relief of symptoms in asthma. There has been concern that excessive uncontrolled …
Pharmacological management of mild or moderate persistent asthma
PM O'Byrne, K Parameswaran - The Lancet, 2006 - thelancet.com
Patients with mild persistent asthma rarely see their doctor with symptoms of the disease.
Partly as a result of this situation, mild asthma is generally undertreated. Findings of several …
Partly as a result of this situation, mild asthma is generally undertreated. Findings of several …
Major reduction in asthma morbidity and continued reduction in asthma mortality in New Zealand: what lessons have been learned?
J Garrett, J Kolbe, G Richards, T Whitlock, H Rea - Thorax, 1995 - thorax.bmj.com
Increasing financial barriers to primary health care against a background of social and
economic decline are likely to have contributed to asthma morbidity and mortality in New …
economic decline are likely to have contributed to asthma morbidity and mortality in New …