[HTML][HTML] Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

[HTML][HTML] Translational medicine for acute lung injury

J Zhang, Y Guo, M Mak, Z Tao - Journal of Translational Medicine, 2024 - Springer
Acute lung injury (ALI) is a complex disease with numerous causes. This review begins with
a discussion of disease development from direct or indirect pulmonary insults, as well as …

An inhalable hybrid biomimetic nanoplatform for sequential drug release and remodeling lung immune homeostasis in acute lung injury treatment

C Liu, L Xi, Y Liu, JCW Mak, S Mao, Z Wang, Y Zheng - ACS nano, 2023 - ACS Publications
Interactions of lung macrophages and recruited neutrophils with the lung microenvironment
continuously aggravate the dysregulation of lung inflammation in the pathogenesis of acute …

Protein Coronas Derived from Mucus Act as Both Spear and Shield to Regulate Transferrin Functionalized Nanoparticle Transcellular Transport in Enterocytes

D Yang, Y Feng, Y Yuan, L Zhang, Y Zhou… - ACS …, 2024 - ACS Publications
The epithelial mucosa is a key biological barrier faced by gastrointestinal, intraoral,
intranasal, ocular, and vaginal drug delivery. Ligand-modified nanoparticles demonstrate …

Emerging application of nanomedicine-based therapy in acute respiratory distress syndrome

Y Xu, L Lv, Q Wang, Q Yao, L Kou, H Zhang - Colloids and Surfaces B …, 2024 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious lung
injuries caused by various factors, leading to increased permeability of the alveolar-capillary …

[HTML][HTML] New therapeutics for extracellular vesicles: delivering CRISPR for cancer treatment

B Yan, Y Liang - International Journal of Molecular Sciences, 2022 - mdpi.com
Cancers are defined by genetic defects, which underlines the prospect of using gene
therapy in patient care. During the past decade, CRISPR technology has rapidly evolved …

Preparation of Budesonide-Loaded Liposomal Nanoparticles for Pulmonary Delivery and Their Therapeutic Effect in OVA-Induced Asthma in Mice

X Zuo, Y Gu, X Guo, W Zheng, H Zheng… - International journal …, 2024 - Taylor & Francis
Purpose Inhaled corticosteroids, including budesonide (BUD), are widely employed for the
treatment of asthma. However, the frequent use of corticosteroids is associated with …

[HTML][HTML] Discovery, validation, and prodrug design of an ACE2 activator for treating bacterial infection-induced lung inflammation

P Lu, F Leslie, H Wang, A Sodhi, C Choi… - Journal of Controlled …, 2023 - Elsevier
Exacerbated inflammatory responses can be detrimental and pose fatal threats to the host,
as exemplified by the global impact of the COVID-19 pandemic, resulting in millions of …

Therapeutic effects of tea polyphenol-loaded nanoparticles coated with platelet membranes on LPS-induced lung injury

H Jin, Y Zhao, Y Yao, J Zhao, R Luo, S Fan… - Biomaterials …, 2023 - pubs.rsc.org
Patients with ALI (acute lung injury)/ARDS (acute respiratory distress syndrome) are often
septic and with poor prognosis, which leads to a high mortality rate of 25–40%. Despite the …

[HTML][HTML] Molecular mechanisms related to responses to oxidative stress and antioxidative therapies in COVID-19: a systematic review

EE Tsermpini, U Glamočlija, F Ulucan-Karnak… - Antioxidants, 2022 - mdpi.com
The coronavirus disease (COVID-19) pandemic is a leading global health and economic
challenge. What defines the disease's progression is not entirely understood, but there are …