Transcriptional profiling of circulating mononuclear cells from patients with chronic obstructive pulmonary disease receiving mesenchymal stromal cell infusions
JD Armitage, DBA Tan, M Sturm… - Stem Cells …, 2021 - academic.oup.com
Chronic obstructive pulmonary disease (COPD) is an inflammatory airways disease with
limited therapeutic options. We have previously shown that mesenchymal stromal cell (MSC) …
limited therapeutic options. We have previously shown that mesenchymal stromal cell (MSC) …
Multiparametric quantitative imaging biomarker as a multivariate descriptor of health: a roadmap
DL Raunig, GA Pennello, JG Delfino, AJ Buckler… - Academic radiology, 2023 - Elsevier
Multiparametric quantitative imaging biomarkers (QIBs) offer distinct advantages over single,
univariate descriptors because they provide a more complete measure of complex …
univariate descriptors because they provide a more complete measure of complex …
The potential of digital molecular diagnostics for infectious diseases in sub-Saharan Africa
Digital Diagnostics for Africa Network - PLOS Digital Health, 2022 - journals.plos.org
There is a large gap between diagnostic needs and diagnostic access across much of sub-
Saharan Africa (SSA), particularly for infectious diseases that inflict a substantial burden of …
Saharan Africa (SSA), particularly for infectious diseases that inflict a substantial burden of …
Development of multiple biomarker panels for prediction of sarcopenia in community-dwelling older adults
Background It is required to consider multiple biomarkers simultaneously to predict
sarcopenia and to understand its complex pathological mechanisms. This study aimed to …
sarcopenia and to understand its complex pathological mechanisms. This study aimed to …
Biomarkers of acute lung injury the individualized approach: for phenotyping, risk stratification and treatment surveillance
DD Murray, TS Itenov, P Sivapalan, JV Eklöf… - Journal of clinical …, 2019 - mdpi.com
Do we need biomarkers of lung damage and infection: For what purpose and how should
they be used properly? Biomarkers of lung damage can be used for diagnosis, risk …
they be used properly? Biomarkers of lung damage can be used for diagnosis, risk …
Real-world use of rescue inhaler sensors, electronic symptom questionnaires and physical activity monitors in COPD
R Bowler, M Allinder, S Jacobson… - BMJ Open …, 2019 - bmjopenrespres.bmj.com
Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease
characterised by airflow obstruction and other morbidities such as respiratory symptoms …
characterised by airflow obstruction and other morbidities such as respiratory symptoms …
Plasma sRAGE levels strongly associate with centrilobular emphysema assessed by HRCT scans
Background There is a strong need for biomarkers to better characterize individuals with
COPD and to take into account the heterogeneity of COPD. The blood protein sRAGE has …
COPD and to take into account the heterogeneity of COPD. The blood protein sRAGE has …
Affimers as an alternative to antibodies in an affinity LC–MS assay for quantification of the soluble receptor of advanced glycation end-products (sRAGE) in human …
F Klont, M Hadderingh, P Horvatovich… - Journal of proteome …, 2018 - ACS Publications
Antibodies are indispensable tools in biomedical research, but their size, complexity, and
sometimes lack of reproducibility created a need for the development of alternative binders …
sometimes lack of reproducibility created a need for the development of alternative binders …
Association of air pollution exposure with exercise-induced oxygen desaturation in COPD
KY Lee, SM Wu, HY Kou, KY Chen, HC Chuang… - Respiratory …, 2022 - Springer
Background There is a link between exposure to air pollution and the increased prevalence
of chronic obstructive pulmonary disease (COPD) and declining pulmonary function, but the …
of chronic obstructive pulmonary disease (COPD) and declining pulmonary function, but the …
Predicting Lung Function Using Biomarkers in Alpha-1 Antitrypsin Deficiency
Lung disease progression in alpha-1 antitrypsin deficiency (AATD) is heterogenous and
manifests in different ways. Blood biomarkers are an attractive method of monitoring …
manifests in different ways. Blood biomarkers are an attractive method of monitoring …