Background: Surfactant protein D (SFTPD) is a lung specific protein which performs several
key regulatory processes to maintain overall lung function. Several infectious and immune …

Background Under the Food and Drug Administration's drug development tool qualification
program, fibrinogen is the first biomarker drug development tool used in chronic obstructive …

Blood-based biomarkers for diagnosing and determining the progression of COPD remain
disappointingly elusive. Although there have been some advances in nonblood-based …

Background The inflammatory biomarker soluble urokinase plasminogen activator receptor
(suPAR) is elevated in severe acute and chronic medical conditions and has been …

In recent years, there has been a great deal of interest in the identification and validation of
blood-based biomarkers for clinical use in chronic obstructive pulmonary disease (COPD) …

Rationale: Emphysema is a chronic obstructive pulmonary disease phenotype with
important prognostic implications. Identifying blood-based biomarkers of emphysema will …

Introduction Soluble urokinase-type plasminogen activator receptor (suPAR) is upregulated
by inflammation and plays a role in the pathogenesis of atherosclerosis. Chronic obstructive …

Background Fibrinogen is increasingly being studied as an inflammatory biomarker in
chronic obstructive pulmonary disease (COPD), but there are limited data on the role of …

Objective Chronic obstructive pulmonary disease (COPD) and coronary artery disease
(CAD) are leading causes of global morbidity and mortality. There is a well-known …

Background We organized this study in order to investigate differences in serum
inflammatory profiles and circulating serum pneumoproteins between smokers with and …