Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and …

C Perrino, P Ferdinandy, HE Bøtker… - Cardiovascular …, 2021 - academic.oup.com
Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and
morbidity in both men and women. Sex, however, affects several aspects of IHD, including …

NLRP3 inflammasome in acute myocardial infarction

AG Mauro, A Bonaventura, E Mezzaroma… - Journal of …, 2019 - journals.lww.com
Acute myocardial infarction (AMI) is associated with the induction of a sterile inflammatory
response that leads to further injury. The NACHT, leucine-rich repeat, and pyrin domain …

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

TJ Park, JH Park, GS Lee, JY Lee, JH Shin… - Cell death & …, 2019 - nature.com
Ischaemic heart disease (IHD) is the leading cause of death worldwide. Although myocardial
cell death plays a significant role in myocardial infarction (MI), its underlying mechanism …

[HTML][HTML] Effects of curcumin nanoparticles in isoproterenol-induced myocardial infarction

PM Boarescu, I Chirilă, AE Bulboacă… - … medicine and cellular …, 2019 - hindawi.com
Curcumin has anti-inflammatory, antioxidative, anticarcinogenic, and cardiovascular
protective effects. Our study is aimed at evaluating the effects of pretreatment with curcumin …

The role of mitochondrial abnormalities in diabetic cardiomyopathy

SA Dabravolski, NK Sadykhov, AG Kartuesov… - International Journal of …, 2022 - mdpi.com
Diabetic cardiomyopathy (DCM) is defined as the presence in diabetic patients of abnormal
cardiac structure and performance (such as left ventricular hypertrophy, fibrosis, and …

Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway

Y Zhuo, R Yuan, X Chen, J He, Y Chen, C Zhang… - Chinese Medicine, 2021 - Springer
Abstract Background Tanshinone I (TI) is a primary component of Salvia miltiorrhiza Bunge
(Danshen), which confers a favorable role in a variety of pharmacological activities including …

Curcumin nanoparticles protect against isoproterenol induced myocardial infarction by alleviating myocardial tissue oxidative stress, electrocardiogram, and biological …

PM Boarescu, I Boarescu, IC Bocșan, RM Pop… - Molecules, 2019 - mdpi.com
Curcumin from Curcuma longa is a nutraceutical compound reported to possess strong
antioxidant activity that makes it a candidate for use in counteracting oxidative stress …

Estrogen receptors: therapeutic perspectives for the treatment of cardiac dysfunction after myocardial infarction

JS da Silva, TL Montagnoli, BS Rocha… - International Journal of …, 2021 - mdpi.com
Estrogen receptors (ER) mediate functions beyond their endocrine roles, as modulation of
cardiovascular, renal, and immune systems through anti-inflammatory and anti-apoptotic …

Curcumin ameliorated myocardial infarction by inhibition of cardiotoxicity in the rat model

M Rahnavard, M Hassanpour, M Ahmadi… - Journal of cellular …, 2019 - Wiley Online Library
Cardiovascular diseases are the main cause of death globally. Many attempts have been
done to ameliorate the pathological changes after the occurrence of myocardial infarction …

Role of RIPK3‑CaMKII‑mPTP signaling pathway‑mediated necroptosis in cardiovascular diseases

S Chen, S Guan, Z Yan, F Ouyang… - International …, 2023 - spandidos-publications.com
Necroptosis, which is distinct from apoptosis and necrosis, serves a crucial role in ontogeny
and the maintenance of homeostasis. In the last decade, it has been demonstrated that the …