Aspergillus fumigatus is a saprotrophic filamentous fungus and also the most prevalent
airborne fungal pathogen of humans. Depending on the host's immune status, the variety of …

Pathogenic fungi have developed many strategies to evade the host immune system.
Multiple escape mechanisms appear to function together to inhibit attack by the various …

Aspergillus fumigatus forms ubiquitous airborne conidia that humans inhale on a daily basis.
Although respiratory fungal infection activates the adaptor proteins CARD9 and MyD88 via …

Host cell death is a critical component of innate immunity and often determines the
progression and outcome of infections. The opportunistic human pathogen Aspergillus …

Aspergillus fumigatus is a model fungal pathogen and a common cause of infection in
individuals with the primary immunodeficiency chronic granulomatous disease (CGD) …

Invasive infections by the human pathogenic fungus Aspergillus fumigatus start with the
outgrowth of asexual, airborne spores (conidia) into the lung tissue of immunocompromised …

Aspergillus fumigatus is the most important air-borne pathogenic fungus of humans. Upon
inhalation of conidia, the fungus makes close contact with lung epithelial cells, which only …

Invasive aspergillosis is a significant threat to health and is a major cause of mortality in
immunocompromised individuals. Understanding the interaction between the fungus and …

Fungal infections are a cause of morbidity in humans, and despite the availability of a range
of antifungal treatments, the mortality rate remains unacceptably high. Although our …

Melanin is an Aspergillus flavus cell wall component that provides chemical and physical
protection to the organism. However, the molecular and biological mechanisms modulating …