Staphylococcus aureus and its food poisoning toxins: characterization and outbreak investigation

JA Hennekinne, ML De Buyser… - FEMS microbiology …, 2012 - academic.oup.com
Staphylococcal food poisoning (SFP) is one of the most common food-borne diseases and
results from the ingestion of staphylococcal enterotoxins (SEs) preformed in food by …

Superantigens, a paradox of the immune response

S Noli Truant, DM Redolfi, MB Sarratea, EL Malchiodi… - Toxins, 2022 - mdpi.com
Staphylococcal enterotoxins are a wide family of bacterial exotoxins with the capacity to
activate as much as 20% of the host T cells, which is why they were called superantigens …

Allergy—A New Role for T Cell Superantigens of Staphylococcus aureus?

G Abdurrahman, F Schmiedeke, C Bachert, BM Bröker… - Toxins, 2020 - mdpi.com
Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …

Peptidoglycan recognition protein–peptidoglycan complexes increase monocyte/macrophage activation and enhance the inflammatory response

MC De Marzi, M Todone, MB Ganem, Q Wang… - …, 2015 - Wiley Online Library
Peptidoglycan recognition proteins (PGRP) are pattern recognition receptors that can bind
or hydrolyse peptidoglycan (PGN). Four human PGRP have been described: PGRP‐S …

A comprehensive look into the volatile exometabolome of enteroxic and non-enterotoxic Staphylococcus aureus strains

I Baptista, M Santos, A Rudnitskaya, JA Saraiva… - The international journal …, 2019 - Elsevier
Staphylococcal food poisoning is a disease that originates significant health and economic
losses and is caused by Staphylococcus aureus strains able to produce enterotoxins. The …

RosettaSurf—A surface-centric computational design approach

A Scheck, S Rosset, M Defferrard… - PLOS Computational …, 2022 - journals.plos.org
Proteins are typically represented by discrete atomic coordinates providing an accessible
framework to describe different conformations. However, in some fields proteins are more …

Structure of staphylococcal enterotoxin E in complex with TCR defines the role of TCR loop positioning in superantigen recognition

KEJ Rödström, P Regenthal, K Lindkvist-Petersson - Plos one, 2015 - journals.plos.org
T cells are crucial players in cell-mediated immunity. The specificity of their receptor, the T
cell receptor (TCR), is central for the immune system to distinguish foreign from host …

Uptake and intracellular trafficking of superantigens in dendritic cells

MB Ganem, MC De Marzi, MJ Fernández-Lynch… - PLoS …, 2013 - journals.plos.org
Bacterial superantigens (SAgs) are exotoxins produced mainly by Staphylococcus aureus
and Streptococcus pyogenes that can cause toxic shock syndrome (TSS). According to …

Heterologous Chimeric Construct Comprising a Modified Bacterial Superantigen and a Cruzipain Domain Confers Protection Against Trypanosoma cruzi Infection

MB Antonoglou, A Sánchez Alberti, DM Redolfi… - Frontiers in …, 2020 - frontiersin.org
Chagas disease is an endemic chronic parasitosis in Latin America affecting more than 7
million people. Around 100 million people are currently at risk of acquiring the infection; …

egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation

S Noli Truant, MC De Marzi, MB Sarratea… - Frontiers in …, 2020 - frontiersin.org
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules,
activating as much as 20% of the T cell population and promoting a cytokine storm which …