Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Mesenchymal stem cells (MSCs) are adult stem cells owing to their regenerative potential
and multilineage potency. MSCs have wide-scale applications either in their native cellular …

Systemic infusion of bone marrow mesenchymal stem cells (BMMSCs) yields therapeutic
benefit for a variety of autoimmune diseases, but the underlying mechanisms are poorly …

Abstract T helper 17 (Th17), a distinct subset of CD4+ T cells with IL-17 as their major
cytokine, orchestrate the pathogenesis of inflammatory and autoimmune diseases …

Summary 2018 was the year of the first marketing authorization of an allogeneic stem cell
therapy by the European Medicines Agency. The authorization concerns the use of …

Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with
multilineage potential to differentiate into cell types of mesodermal origin, such as …

It is estimated that, of the 7.9 million fractures sustained in the United States each year, 5%
to 20% result in delayed or impaired healing requiring therapeutic intervention. Following …

Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …

Objective Current approaches offer no cures for rheumatoid arthritis (RA). Accumulating
evidence has revealed that manipulation of bone marrow–derived mesenchymal stem cells …

Critical bone defects and related delayed union and nonunion are still worldwide problems
to be solved. Bone tissue engineering is mainly aimed at achieving satisfactory bone …