Animal models of hidden hearing loss: Does auditory-nerve-fiber loss cause real-world listening difficulties?

KS Henry - Molecular and Cellular Neuroscience, 2022 - Elsevier
Afferent innervation of the cochlea by the auditory nerve declines during aging and
potentially after sound overexposure, producing the common pathology known as cochlear …

Intracortical microelectrode array unit yield under chronic conditions: a comparative evaluation

JO Usoro, BS Sturgill, KC Musselman, JR Capadona… - Micromachines, 2021 - mdpi.com
While microelectrode arrays (MEAs) offer the promise of elucidating functional neural
circuitry and serve as the basis for a cortical neuroprosthesis, the challenge of designing …

Normal tone-in-noise sensitivity in trained budgerigars despite substantial auditory-nerve injury: no evidence of hidden hearing loss

KS Henry, KS Abrams - Journal of Neuroscience, 2021 - Soc Neuroscience
Loss of auditory-nerve (AN) afferent cochlear innervation is a prevalent human condition that
does not affect audiometric thresholds and therefore remains largely undetectable with …

Midbrain-level neural correlates of behavioral tone-in-noise detection: dependence on energy and envelope cues

Y Wang, KS Abrams, LH Carney… - Journal of …, 2021 - Soc Neuroscience
Hearing in noise is a problem often assumed to depend on encoding of energy level by
channels tuned to target frequencies, but few studies have tested this hypothesis. The …

Midbrain synchrony to envelope structure supports behavioral sensitivity to single-formant vowel-like sounds in noise

KS Henry, KS Abrams, J Forst, MJ Mender… - Journal of the …, 2017 - Springer
Vowels make a strong contribution to speech perception under natural conditions. Vowels
are encoded in the auditory nerve primarily through neural synchrony to temporal fine …

Histological Correlates of Auditory Nerve Injury from Kainic Acid in the Budgerigar (Melopsittacus undulatus)

Y Wang, KS Abrams, M Youngman… - Journal of the Association …, 2023 - Springer
Purpose Loss of auditory nerve afferent synapses with cochlear hair cells, called cochlear
synaptopathy, is a common pathology in humans caused by aging and noise overexposure …

Mechanisms of masking by Schroeder-phase harmonic tone complexes in the budgerigar (Melopsittacus undulatus)

KS Henry, Y Wang, KS Abrams, LH Carney - Hearing Research, 2023 - Elsevier
Schroeder-phase harmonic tone complexes can have a flat temporal envelope and rising or
falling instantaneous-frequency sweeps within F0 periods, depending on the phase-scaling …

Effects of selective auditory-nerve damage on the behavioral audiogram and temporal integration in the budgerigar

SJ Wong, KS Abrams, KN Amburgey, Y Wang… - Hearing research, 2019 - Elsevier
Auditory-nerve fibers are lost steadily with age and as a possible consequence of noise-
induced glutamate excitotoxicity. Auditory-nerve loss in the absence of other cochlear …

Psychometric and subcortical neurometric measures of temporal discrimination in rhesus macaques

CA Mackey, S Hauser, AM Schoenhaut, N Temghare… - BioRxiv, 2022 - biorxiv.org
Temporal envelope fluctuations are abundant in nature and are critical for perception of
complex sounds. While psychophysical sinusoidal amplitude modulation (SAM) processing …

Amplitude modulation detection in children with a history of temporary conductive hearing loss remains impaired for years after restoration of normal hearing

M McKenna Benoit, M Orlando, K Henry… - Journal of the Association …, 2019 - Springer
Otitis media with effusion (OME) is considered a form of relative sensory deprivation that
often occurs during a critical period of language acquisition in children. Animal studies have …