Dihydrochalcones: occurrence in the plant kingdom, chemistry and biological activities

C Riviere - Studies in natural products chemistry, 2016 - Elsevier
Dihydrochalcones (DHCs), a class of minor flavonoids, have two aromatic rings linked by a
three-carbon bridge that is saturated, as distinct from chalcones. They occur with a limited …

Insight into the IgE-binding sites of allergenic peptides of tropomyosin in shrimp (Penaeus chinensis) induced by cold plasma active particles

JH Cheng, H Wang, DW Sun - International Journal of Biological …, 2023 - Elsevier
Tropomyosin (TM) is a major allergen in crustaceans, and its allergenicity mainly depends
on epitopes. In this study, the locations of IgE-binding sites between plasma active particles …

Mechanisms underlying the xanthine oxidase inhibitory effects of dietary flavonoids galangin and pinobanksin

Y Dong, H Huang, M Zhao, D Sun-Waterhouse… - Journal of Functional …, 2016 - Elsevier
Xanthine oxidase (XOD) inhibitory activities of five dietary flavonoids pinobanksin, galangin,
pinocembrin, pinocembrin-7-O-β-d-glucopyranoside and glabranin were evaluated. Enzyme …

Caffeoylquinic acids competitively inhibit pancreatic lipase through binding to the catalytic triad

B Hu, F Cui, F Yin, X Zeng, Y Sun, Y Li - International journal of biological …, 2015 - Elsevier
Caffeoylquinic acid and its isomers inhibited porcine Pancreatic Lipase (PL) activity
according to a competitive mode where binding and interaction with the catalytic triad of …

Screening of potential inhibitors targeting the main protease structure of SARS-CoV-2 via molecular docking

X Yang, X Xing, Y Liu, Y Zheng - Frontiers in Pharmacology, 2022 - frontiersin.org
The novel coronavirus disease (COVID-19) caused by SARS-CoV-2 virus spreads rapidly to
become a global pandemic. Researchers have been working to develop specific drugs to …

A combined experimental and theoretical analysis of the solid-state supramolecular self-assembly of N-(2, 4-dichlorophenyl)-1-naphthamide: Synthesis …

M Kazmi, A Ibrar, HS Ali, M Ghufran, A Wadood… - Journal of Molecular …, 2019 - Elsevier
In the present report, we describe the synthesis of the amide derivative, N-(2, 4-
dichlorophenyl)-1-naphthamide, 3, via a facile chemical route. The title compound was …

Discovery of potential neurodegenerative inhibitors in Alzheimer's disease by casein kinase 1 structure-based virtual screening

RP Rodrigues, CHTP Silva - Medicinal Chemistry Research, 2017 - Springer
Alzheimer's disease is a progressive neurodegenerative disorder characterized by loss of
neurons. Pathological patterns include the presence of amyloid plaques (accumulation of …

Influence of substrates on the in vitro kinetics of steviol glucuronidation and interaction between steviol glycosides metabolites and UGT2B7

JM Chen, YM Xia, YD Zhang, TT Zhang… - … Journal of Food …, 2018 - Taylor & Francis
Steviol glycosides, a natural sweetener, may perform bioactivities via steviol, their main
metabolite in human digestion. The metabolising kinetics, ie glucuronidation kinetics and …

A thermoregulated phase-transfer ruthenium nanocatalyst for the atmospheric hydrogenation of α, β-unsaturated ketones

B Gao, Y Wang - Journal of Chemical Research, 2023 - journals.sagepub.com
The selective hydrogenation of chalcone to dihydrochalcone under atmospheric hydrogen
pressure is investigated using a thermoregulated phase-transfer ruthenium nanocatalyst …

Hetero-tricyclic lead scaffold as novel PDE5A inhibitor for antihypertensive activity: in silico docking studies

DP Mali, NM Bhatia - Current Computer-Aided Drug Design, 2019 - ingentaconnect.com
Objective: To screen the phytochemicals for phosphodiesterase 5A (PDE5A) inhibitory
potential and identify lead scaffolds of antihypertensive phytochemicals using in silico …