Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …

Vaccines represent the single most cost-efficient and equitable way to combat and eradicate
infectious diseases. While traditional licensed vaccines consist of either …

The human genetic code encrypted in thousands of genes holds the secret for synthesis of
proteins that drive all biological processes necessary for normal life and death. Though the …

With rapid advances in understanding molecular pathogenesis of human diseases in the era
of genome sciences and systems biology, it is anticipated that increasing numbers of …

Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

Particulate matter (PM) air pollution poses a formidable public health threat to the city of
Beijing. Among the various hazards of PM pollutants, microorganisms in PM2. 5 and PM10 …

Introduction: National Institutes of Health (NIH) defines gene therapy as an experimental
technique that uses genes to treat or prevent disease. Although gene therapy is a promising …

Adenoviruses are large (~ 950 Å) and complex non-enveloped, dsDNA icosahedral viruses.
They have a pseudo-T= 25 triangulation number with at least 12 different proteins …

No matter what their origin, strain and family, viruses have evolved exquisite strategies to
reach and penetrate specific target cells where they hijack the cellular machinery to express …

The superfamily of proteins containing C‐type lectin‐like domains (CTLDs) is a large group
of extracellular Metazoan proteins with diverse functions. The CTLD structure has a …