Simple Summary Glioblastoma is one of the most treatment-refractory human malignancies,
and despite techniques that have allowed scientists and clinicians to better understand the …

The janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling
pathway is associated with the regulation of essential cellular mechanisms, such as …

Abstract Procollagen lysyl hydroxylase 1 (PLOD1) is highly expressed in malignant tumors
such as esophageal squamous cell carcinoma, gastric cancer, and colorectal cancer …

Background Glioma is the most common primary malignant tumor in the central nervous
system with frequent hypoxia and angiogenesis. Limb-Bud and Heart (LBH) is a highly …

Hypoxia, as an important hallmark of the tumor microenvironment, is a major cause of
oxidative stress and plays a central role in various malignant tumors, including glioblastoma …

Background: Aberrant activities of signal transducer and activator of transcription 1 (STAT1)
have been implicated in cancer development. However, the prognostic value of STAT1 …

Significance: Changes in the oxidative balance can affect cellular physiology and adaptation
through redox signaling. The endothelial cells that line blood vessels are particularly …

Malignant gliomas are a heterogeneous group of brain tumors with a poor prognosis, which
is largely due to its aggressive invasiveness and angiogenesis. In recent years, it has been …

Gliomas are the most common type of the malignant brain tumor, which arise from glial cells.
They make up about 40% of all primary brain tumors and around 70% of all primary …

Abstract CPVL (carboxypeptidase, vitellogenic-like) is a serine carboxypeptidase that was
first characterized in human macrophages. However, the function of CPVL remains unclear …