The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder in which recurrent
abdominal pain is associated with defecation or a change in bowel habits (constipation …

Alzheimer's disease (AD), as one of most common dementia, mainly affects older people
from the worldwide. In this study, we intended to explore the possible mechanism of …

The microbiome influences the emotional and cognitive phenotype of its host, as well as the
neurodevelopment and pathophysiology of various brain processes and disorders, via the …

1. Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev
Immunol.(2009) 9: 799–809. doi: 10.1038/nri2653 2. Helander HF, Fändriks L. Surface area …

Irritable bowel syndrome (IBS) is a common disorder characterized by chronic abdominal
pain and changes in bowel movements. Visceral hypersensitivity is thought to be …

Irritable bowel syndrome (IBS), as a functional and psychosomatic disease, reduces the
quality of life and increases the risk of developing mental disorders. Deregulation of the …

Background Psychological stress is a major trigger for visceral hypersensitivity (VH) in
irritable bowel syndrome. The zinc finger protein ZBTB20 (ZBTB20) is implicated in somatic …

This review delves into neuroimmunology, focusing on its relevance to multiple sclerosis
(MS) and potential treatment advancements. Neuroimmunology explores the intricate …

Background and Purpose: Irritable bowel syndrome (IBS) is usually associated with chronic
gastrointestinal disorders. Its most common subtype is accompanied with diarrhea (IBS-D) …