RNA-seq, including bulk RNA-seq and single-cell RNA-seq, is a next-generation
sequencing-based RNA profiling method capable of measuring gene expression patterns …

Single-cell sequencing (SCS) is a fast-growing, exciting field in genomic medicine. It
enables the high-resolution study of cellular heterogeneity, and reveals the molecular basis …

Fascin actin-bundling protein 1 (FSCN1), an actin-bundling protein associated with cell
migration and invasion, is highly expressed in various tumor tissues. FSCN1 has also been …

Current anticancer paradigms largely target driver mutations considered integral for cancer
cell survival and tumor progression. Although initially successful, many of these strategies …

In humans, zinc finger protein 671 (ZNF671) is a type of transcription factor. However, the
contribution of tumor heterogeneity to the functional role of ZNF671 remains unknown. The …

High-dimension single-cell technology is transforming our ability to study and understand
cancer. Numerous studies and reviews have reported advances in technology development …

Activating nuclear factor-erythroid 2-related factor (Nrf2), a master regulator of redox
homeostasis, has been shown to suppress initiation of carcinogenesis in normal cells …

Nowadays, in the field of research the Graphics Processing Units (GPUs) is possibly the
maximum powerful computational hardware. Beside of powerful graphics engine, the …

Single-cell RNA sequencing reveals the gene structure and gene expression status of a
single cell, which can reflect the heterogeneity between cells. However, batch effects caused …

The molecular basis underlying the dedifferentiation of mammalian adult cardiomyocytes
(ACMs) into myocyte-derived cardiac progenitor cells (mCPCs) during cardiac tissue …