Diabetic peripheral neuropathy (DPN) occurs in up to half of individuals with type 1 or type 2
diabetes. DPN results from the distal-to-proximal loss of peripheral nerve function, leading to …

Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by
almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids …

Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Injury of oligodendrocytes (OLs) induces demyelination, and patients with
neurodegenerative diseases exhibit demyelination concomitantly with neurological deficit …

Poor wound healing can seriously affect the health of patients with diabetes and result in a
heavy medical burden. Recently, exosomes have been considered the key substances …

Diabetes prevalence continues to climb with the aging population. Type 2 diabetes (T2D),
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …

Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

Extracellular vesicles (EVs) are membrane-delimited particles that are secreted by nearly all
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …

Exosomes are extracellular vesicles released by the vast majority of cell types both in vivo
and ex vivo, upon the fusion of multivesicular bodies (MVBs) with the cellular plasma …

Diabetic peripheral neuropathy (DPN) is one of the most prevalent chronic complications of
diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal …