Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

[HTML][HTML] The how's and what's of vaccine reactogenicity

C Hervé, B Laupèze, G Del Giudice, AM Didierlaurent… - npj Vaccines, 2019 - nature.com
Reactogenicity represents the physical manifestation of the inflammatory response to
vaccination, and can include injection-site pain, redness, swelling or induration at the …

[HTML][HTML] The anatomy of pain and suffering in the brain and its clinical implications

D De Ridder, D Adhia, S Vanneste - Neuroscience & Biobehavioral …, 2021 - Elsevier
Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

[HTML][HTML] Microglia and beyond: innate immune cells as regulators of brain development and behavioral function

KM Lenz, LH Nelson - Frontiers in immunology, 2018 - frontiersin.org
Innate immune cells play a well-documented role in the etiology and disease course of
many brain-based conditions, including multiple sclerosis, Alzheimer's disease, traumatic …

[HTML][HTML] How biological sex of the host shapes its gut microbiota

F Valeri, K Endres - Frontiers in Neuroendocrinology, 2021 - Elsevier
The gut microbiota is a complex system, consisting of a dynamic population of
microorganisms, involved in the regulation of the host's homeostasis. A vast number of …

[HTML][HTML] Microglia morphophysiological diversity and its implications for the CNS

A Vidal-Itriago, RAW Radford, JA Aramideh… - Frontiers in …, 2022 - frontiersin.org
Microglia are mononuclear phagocytes of mesodermal origin that migrate to the central
nervous system (CNS) during the early stages of embryonic development. After colonizing …

Sex differences in the human brain: a roadmap for more careful analysis and interpretation of a biological reality

AR DeCasien, E Guma, S Liu, A Raznahan - Biology of Sex Differences, 2022 - Springer
The presence, magnitude, and significance of sex differences in the human brain are hotly
debated topics in the scientific community and popular media. This debate is largely fueled …

[PDF][PDF] Microbiota-brain interactions: Moving toward mechanisms in model organisms

J Nagpal, JF Cryan - Neuron, 2021 - cell.com
Changes in the microbiota are associated with alterations in nervous system structure-
function and behavior and have been implicated in the etiology of neuropsychiatric and …

Probiotics: Potential novel therapeutics for microbiota-gut-brain axis dysfunction across gender and lifespan

S Snigdha, K Ha, P Tsai, TG Dinan, JD Bartos… - Pharmacology & …, 2022 - Elsevier
Probiotics are live microorganisms, which when administered in adequate amounts, present
a health benefit for the host. While the beneficial effects of probiotics on gastrointestinal …

Estrogens and phytoestrogens in body functions

I Ceccarelli, L Bioletti, S Peparini, E Solomita… - Neuroscience & …, 2022 - Elsevier
Estrogens are the hormones of reproduction in women as well as of many other important
functions in the male and female body. They undergo significant changes in the different …