Sex differences in metabolism and cardiometabolic disorders

KC Krishnan, M Mehrabian… - Current opinion in …, 2018 - journals.lww.com
Sex differences in body fat distribution, glucose homeostasis, insulin signaling, ectopic fat
accumulation, and lipid metabolism during normal growth and in response to hormonal or …

Age and sex: impact on adipose tissue metabolism and inflammation

M Varghese, J Song, K Singer - Mechanisms of ageing and development, 2021 - Elsevier
Age associated chronic inflammation is a major contributor to diseases with advancing age.
Adipose tissue function is at the nexus of processes contributing to age-related metabolic …

Adipocyte metabolism and health after the menopause: The role of exercise

ML Marsh, MN Oliveira, VJ Vieira-Potter - Nutrients, 2023 - mdpi.com
Postmenopausal women represent an important target population in need of preventative
cardiometabolic approaches. The loss of estrogen following the menopause eliminates …

Associations between exposure to brominated flame retardants and metabolic syndrome and its components in US adults

Z Che, H Jia, R Chen, K Pan, Z Fan, C Su, Z Wu… - Science of The Total …, 2023 - Elsevier
Background Humans are simultaneously exposed to numerous of environmental
brominated flame retardants (BFRs). We aim to explore the overall associations of BFRs …

[HTML][HTML] Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase

R Ye, QA Wang, C Tao, L Vishvanath, M Shao… - Molecular …, 2015 - Elsevier
Background The selective estrogen receptor modulator tamoxifen, in combination with the
Cre-ER T2 fusion protein, has been one of the mainstream methods to induce genetic …

Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle

A Sacharidou, K Chambliss, J Peng, J Barrera… - Nature …, 2023 - nature.com
The estrogen receptor (ER) designated ERα has actions in many cell and tissue types that
impact glucose homeostasis. It is unknown if these include mechanisms in endothelial cells …

Role of estrogen in the regulation of central and peripheral energy homeostasis: from a menopausal perspective

J Zhu, Y Zhou, B Jin, J Shu - Therapeutic Advances in …, 2023 - journals.sagepub.com
Estrogen plays a prominent role in regulating and coordinating energy homeostasis
throughout the growth, development, reproduction, and aging of women. Estrogen receptors …

Estrogens and the control of energy homeostasis: a brain perspective

M Lopez, M Tena-Sempere - Trends in Endocrinology & Metabolism, 2015 - cell.com
Despite their prominent roles in the control of reproduction, estrogens pervade many other
bodily functions. Key metabolic pathways display marked sexual differences, and estrogens …

Sex hormones and cardiometabolic health: role of estrogen and estrogen receptors

D Clegg, AL Hevener, KL Moreau, E Morselli… - …, 2017 - academic.oup.com
With increased life expectancy, women will spend over three decades of life
postmenopause. The menopausal transition increases susceptibility to metabolic diseases …

The role of estrogens in the adipose tissue milieu

JR Bracht, VJ Vieira‐Potter… - Annals of the New …, 2020 - Wiley Online Library
One of the leading causes for the development of adverse metabolic effects, including type 2
diabetes, dyslipidemia, and cardiovascular diseases, is the accumulation of excess body …