CCDC (coiled-coil domain-containing) is a coiled helix domain that exists in natural proteins.
There are about 180 CCDC family genes, encoding proteins that are involved in intercellular …

Cancer is the world's second leading cause of mortality and one of the major public health
problems. Cancer incidence and mortality rates remain high despite the great …

Prostate cancer (PCa) is the most commonly diagnosed cancer in males in the Western
world. Although prostate-specific antigen (PSA) has been widely used as a biomarker for …

Associations between epigenetic alterations and disease status have been identified for
many diseases. However, there is no strong evidence that epigenetic alterations are directly …

Cilia are essential to many diverse cellular processes. Although many major axonemal
components have been identified and studied, how they interact to form a functional …

Current diagnostic and prognostic tools for prostate cancer (PC) are suboptimal, leading to
overdiagnosis and overtreatment. Aberrant promoter hypermethylation of specific genes has …

Background Prognostic tools for prostate cancer (PC) are inadequate and new molecular
biomarkers may improve risk stratification. The epigenetic mark 5-hydroxymethylcytosine …

Multicomponent molecular modifications such as DNA methylation may offer sensitive and
specific cervical intraepithelial neoplasia and cervical cancer biomarkers. In this study, we …

Biomarkers can improve prostate cancer diagnosis and treatment. Accuracy of prostate-
specific antigen (PSA) for early diagnosis of prostate cancer is not satisfactory, as it is an …

Abstract Background Prostate cancer (PCa) remains the second leading cause of deaths
due to cancer in the United States in men. The aim of this study was to perform an integrative …