• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Compared with the extensive data on left‐sided infective endocarditis (IE), there is much
less published information on the features and management of right‐sided IE. Right‐sided …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Background and Purpose—Stroke mortality has been declining since the early 20th century.
The reasons for this are not completely understood, although the decline is welcome. As a …

The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

About half of all nosocomial infections are associated with indwelling devices. Infections
associated with implanted surgical devices are particularly difficult to deal with because they …

Bacterial colonization in the form of biofilms on surfaces causes persistent infections and is
an issue of considerable concern to healthcare providers. There is an urgent need for novel …

The ACC and the AHA have long been involved in the joint development of practice
guidelines designed to assist healthcare providers in the management of selected …

The ACC and the AHA have long been involved in the joint development of practice
guidelines designed to assist healthcare providers in the management of selected …

rin. 25, 26 Inhibition of S-warfarin metabolism is more important clinically because this
isomer is 5 times more potent than the R-isomer as a vitamin K antagonist. 25, 26 …