The haptoglobin‐CD163‐heme oxygenase‐1 pathway for hemoglobin scavenging

JH Thomsen, A Etzerodt, P Svendsen… - … medicine and cellular …, 2013 - Wiley Online Library
The haptoglobin‐(Hp‐) CD163‐heme oxygenase‐1 (HO‐1) pathway is an efficient captor‐
receptor‐enzyme system to circumvent the hemoglobin (Hb)/heme‐induced toxicity during …

Dysregulation of iron metabolism in cardiovascular diseases: From iron deficiency to iron overload

Y Bi, A Ajoolabady, LJ Demillard, W Yu… - Biochemical …, 2021 - Elsevier
Iron deficiency and iron overload are the most prevalent and opposite forms of dysregulated
iron metabolism that affect approximately 30 percent of the world population, in particularly …

High-carbohydrate, high-fat diet–induced metabolic syndrome and cardiovascular remodeling in rats

SK Panchal, H Poudyal, A Iyer, R Nazer… - Journal of …, 2011 - journals.lww.com
The prevalence of metabolic syndrome including central obesity, insulin resistance,
impaired glucose tolerance, hypertension, and dyslipidemia is increasing. Development of …

Pulmonary rehabilitation improves heart rate variability at peak exercise, exercise capacity and health-related quality of life in chronic obstructive pulmonary disease

ST Cheng, YK Wu, MC Yang, CY Huang, HC Huang… - Heart & Lung, 2014 - Elsevier
Objective Patients with chronic obstructive pulmonary disease (COPD) appear to have
impaired cardiac autonomic modulation with depressed heart rate variability (HRV) …

Targeting the Nrf2/ARE signalling pathway to mitigate isoproterenol‐induced cardiac hypertrophy: Plausible role of hesperetin in redox homeostasis

P Velusamy, T Mohan, DB Ravi… - Oxidative medicine …, 2020 - Wiley Online Library
Cardiac hypertrophy is the underlying cause of heart failure and is characterized by
excessive oxidative stress leading to collagen deposition. Therefore, understanding the …

[HTML][HTML] Antioxidant and cytoprotective effects of L-Serine on human endothelial cells

MN Maralani, A Movahedian… - Research in …, 2012 - ncbi.nlm.nih.gov
Oxidative stress has been implicated as a prominent determinant in the development of
several diseases such as atherosclerosis. Anti atherosclerotic effects of L-serine have been …

Low-dose immune challenges result in detectable levels of oxidative damage

EM Armour, TL Bruner, JK Hines… - Journal of …, 2020 - journals.biologists.com
Infection can result in substantial costs to animals, so they frequently respond by removing
infectious agents with an immune response. However, immune responses entail their own …

Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway

J Cao, PL Tsenovoy, EA Thompson, JR Falck… - Prostaglandins & other …, 2015 - Elsevier
Myocardial infarction (MI) is complicated by ventricular fibrosis and associated diastolic and
systolic failure. Emerging studies implicate Wnt1 signaling in the formation of new blood …

Pulmonary rehabilitation improves subjective sleep quality in COPD

CC Lan, HC Huang, MC Yang, CH Lee… - Respiratory …, 2014 - rc.rcjournal.com
BACKGROUND: Poor sleep quality is often reported among patients with COPD. Pulmonary
rehabilitation (PR) is beneficial in improving exercise capacity and health-related quality of …

Effects of heme oxygenase-1 upregulation on blood pressure and cardiac function in an animal model of hypertensive myocardial infarction

T Chen, J Li, L Liu, L Fan, X Li, Y Wang… - International Journal of …, 2013 - mdpi.com
In this study, we evaluate the effect of HO-1 upregulation on blood pressure and cardiac
function in the new model of infarct spontaneous hypertensive rats (ISHR). Male …