Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

UroPathogenic Escherichia coli (UPEC) Infections: Virulence Factors, Bladder Responses, Antibiotic, and Non-antibiotic Antimicrobial Strategies

ME Terlizzi, G Gribaudo, ME Maffei - Frontiers in microbiology, 2017 - frontiersin.org
Urinary tract infections (UTIs) are one of the most common pathological conditions in both
community and hospital settings. It has been estimated that about 150 million people …

ClermonTyping: an easy-to-use and accurate in silico method for Escherichia genus strain phylotyping

J Beghain, A Bridier-Nahmias… - Microbial …, 2018 - microbiologyresearch.org
The genus Escherichia is composed of Escherichia albertii, E. fergusonii, five cryptic
Escherichia clades and E. coli sensu stricto. Furthermore, the E. coli species can be divided …

Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones

L Roer, S Overballe-Petersen, F Hansen, K Schønning… - Msphere, 2018 - Am Soc Microbiol
Escherichia coli sequence type 410 (ST410) has been reported worldwide as an
extraintestinal pathogen associated with resistance to fluoroquinolones, third-generation …

Analysis of the Escherichia coli extracellular vesicle proteome identifies markers of purity and culture conditions

J Hong, P Dauros-Singorenko… - Journal of …, 2019 - Taylor & Francis
Bacteria release nano-sized extracellular vesicles (EVs) into the extracellular milieu.
Bacterial EVs contain molecular cargo originating from the parent bacterium and have …

Intestinal Pathogenic Escherichia coli: Insights for Vaccine Development

M Rojas-Lopez, R Monterio, M Pizza… - Frontiers in …, 2018 - frontiersin.org
Diarrheal diseases are one of the major causes of mortality among children under five years
old and intestinal pathogenic Escherichia coli (InPEC) plays a role as one of the large …

Genomic Survey of E. coli From the Bladders of Women With and Without Lower Urinary Tract Symptoms

A Garretto, T Miller-Ensminger, A Ene… - Frontiers in …, 2020 - frontiersin.org
Urinary tract infections (UTIs) are one of the most common human bacterial infections. While
UTIs are commonly associated with colonization by Escherichia coli, members of this …

Vaccines meet big data: State-of-the-Art and future prospects. From the classical 3Is (“Isolate–Inactivate–Inject”) vaccinology 1.0 to vaccinology 3.0, vaccinomics, and …

NL Bragazzi, V Gianfredi, M Villarini… - Frontiers in public …, 2018 - frontiersin.org
Vaccines are public health interventions aimed at preventing infections-related mortality,
morbidity, and disability. While vaccines have been successfully designed for those …

Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coli

KGK Goh, MD Phan, BM Forde, TM Chong, WF Yin… - MBio, 2017 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract and bloodstream
infections and possesses an array of virulence factors for colonization, survival, and …

Whole-genome comparison of urinary pathogenic Escherichia coli and faecal isolates of UTI patients and healthy controls

KL Nielsen, M Stegger, K Kiil, PA Godfrey… - International Journal of …, 2017 - Elsevier
The faecal flora is a common reservoir for urinary tract infection (UTI), and Escherichia coli
(E. coli) is frequently found in this reservoir without causing extraintestinal infection. We …