Background Hypertension is a substantial public health problem and is a leading risk factor
for cardiovascular diseases and deaths worldwide. Epidemiological studies have …

Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …

The endothelium, as the guardian of vascular homeostasis, is closely related to the
occurrence and development of cardiovascular diseases (CVDs). As an early marker of the …

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that
generate superoxide anion (O 2•-) and hydrogen peroxide (H 2 O 2), and that are widely …

Kaempferol is a natural flavonoid compound that exhibits various pharmacological actions.
However, there are few reports regarding the role of kaempferol in cardiovascular …

This study is aimed to investigate whether tuna protein hydrolysate (TPH) supplementation
could alleviate cardiovascular complications induced by a high-fat diet (HFD) in rats. Rats …

Abstract MT-1207 (MT) as a new antihypertensive drug is under clinical trial. However, its
hypotensive mechanism has not been experimentally explored, and it is unknown whether …

This study investigated the effects of nobiletin on cardiorenal changes and the underlying
mechanisms involved in two-kidney, one-clip (2K-1C) hypertension. 2K-1C rats were treated …

Hypertension is a serious concern as it is one of the causes of kideny failure and pulmonary
fibrosis. An important therapeutic strategy for treating chronic hypertension is to inhibit the …

Renovascular hypertension (RH), a secondary hypertension, can significantly impact heart
health, resulting in heart damage and dysfunction, thereby elevating the risk of …