Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms
R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms that may explain why the sense of smell is lost or altered …
examine potential mechanisms that may explain why the sense of smell is lost or altered …
Prevalence of olfactory dysfunction with the omicron variant of SARS-CoV-2: a systematic review and meta-analysis
CS von Bartheld, L Wang - Cells, 2023 - mdpi.com
The omicron variant is thought to cause less olfactory dysfunction than previous variants of
SARS-CoV-2, but the reported prevalence differs greatly between populations and studies …
SARS-CoV-2, but the reported prevalence differs greatly between populations and studies …
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection
Understanding protective immunity to COVID-19 facilitates preparedness for future
pandemics and combats new SARS-CoV-2 variants emerging in the human population …
pandemics and combats new SARS-CoV-2 variants emerging in the human population …
Viral membrane fusion: a dance between proteins and lipids
There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …
members of high concern for global human health. All enveloped viruses have a dedicated …
[HTML][HTML] Host cell-intrinsic innate immune recognition of SARS-CoV-2
EA Madden, MS Diamond - Current opinion in virology, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged at the end of
2019 and caused the pandemic of coronavirus disease 2019 (COVID-19). Basic and clinical …
2019 and caused the pandemic of coronavirus disease 2019 (COVID-19). Basic and clinical …
Application of machine learning on understanding biomolecule interactions in cellular machinery
Abstract Machine learning (ML) applications have become ubiquitous in all fields of
research including protein science and engineering. Apart from protein structure and …
research including protein science and engineering. Apart from protein structure and …
Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice
AD Kenney, A Zani, J Kawahara, AC Eddy, XL Wang… - EMBO …, 2023 - embopress.org
Interferon‐induced transmembrane protein 3 (IFITM3) is an antiviral protein that alters cell
membranes to block fusion of viruses. Conflicting reports identified opposing effects of …
membranes to block fusion of viruses. Conflicting reports identified opposing effects of …
IFITM protein regulation and functions: Far beyond the fight against viruses
N Friedlová, F Zavadil Kokáš, TR Hupp… - Frontiers in …, 2022 - frontiersin.org
Interferons (IFNs) are important cytokines that regulate immune responses through the
activation of hundreds of genes, including interferon-induced transmembrane proteins …
activation of hundreds of genes, including interferon-induced transmembrane proteins …
Host membranes as drivers of virus evolution
M Matveeva, M Lefebvre, H Chahinian, N Yahi… - Viruses, 2023 - mdpi.com
The molecular mechanisms controlling the adaptation of viruses to host cells are generally
poorly documented. An essential issue to resolve is whether host membranes, and …
poorly documented. An essential issue to resolve is whether host membranes, and …
Post-translational modifications of cGAS-STING: A critical switch for immune regulation
Y Yu, J Liu, C Liu, R Liu, L Liu, Z Yu, J Zhuang, C Sun - Cells, 2022 - mdpi.com
Innate immune mechanisms initiate immune responses via pattern-recognition receptors
(PRRs). Cyclic GMP-AMP synthase (cGAS), a member of the PRRs, senses diverse …
(PRRs). Cyclic GMP-AMP synthase (cGAS), a member of the PRRs, senses diverse …