Organoids are simple tissue-engineered cell-based in vitro models that recapitulate many
aspects of the complex structure and function of the corresponding in vivo tissue. They can …

Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Recapitulation of complex tissues signifies a remarkable challenge and, to date, only a few
approaches have emerged that can efficiently reconstruct necessary gradients in 3D …

The advancement of microfluidics has enabled numerous discoveries and technologies in
life sciences. However, due to the lack of industry standards and configurability, the design …

Natural tissues and organs exhibit an array of spatial gradients, from the polarized neural
tube during embryonic development to the osteochondral interface present at articulating …

The interactions among tumour cells, the tumour microenvironment (TME) and non-tumour
tissues are of interest to many cancer researchers. Micro-engineering approaches and …

The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

Bone is an important part of the human body structure and plays a vital role in human health.
A microfluidic chip that can simulate the structure and function of bone will provide a platform …

To assist the transition of 3D bioprinting technology from simple lab-based tissue fabrication,
to fully functional and implantable organs, the technology must not only provide shape …

Variations in oxygen levels play key roles in numerous physiological and pathological
processes, but are often not properly controlled in in vitro models, introducing a significant …