Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in
molecular imaging using positron emission tomography have provided insights into the time …

A growing body of evidence has demonstrated a link between Alzheimer disease (AD) and
epilepsy. Late-onset epilepsy and epileptiform activity can precede cognitive deterioration in …

Reactive astrocytes play an important role in the development of Alzheimer's disease (AD).
Here, we aimed to investigate the temporospatial relationships among monoamine oxidase …

Purpose Type 2 diabetes mellitus (T2DM) is associated with a greater risk of Alzheimer's
disease. Synaptic impairment and protein aggregates have been reported in the brains of …

Advances in experimental and computational technologies continue to grow rapidly to
provide novel avenues for the treatment of neurodegenerative disorders. Despite this, there …

INTRODUCTION In addition to the accumulation of amyloid plaques and neurofibrillary
tangles, the presence of excess neural activity is a pathological hallmark of Alzheimer's …

Objective We used the lateral fluid percussion injury (LFPI) model of moderatetosevere
traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post …

Animal models of Alzheimer's disease amyloidosis that recapitulate cerebral amyloid-beta
pathology have been widely used in preclinical research and have greatly enabled the …

Slow and progressive loss of retinal ganglion cells (RGCs) is the main characteristic of
glaucoma, the second leading cause of blindness worldwide. Previous studies have shown …

Synaptic vesicle glycoprotein 2A (SV2A) regulates action potential-dependent
neurotransmitter release and is commonly known as the primary binding site of an approved …