Myopia

PN Baird, SM Saw, C Lanca, JA Guggenheim… - Nature reviews Disease …, 2020 - nature.com
Myopia, also known as short-sightedness or near-sightedness, is a very common condition
that typically starts in childhood. Severe forms of myopia (pathologic myopia) are associated …

[HTML][HTML] IMI pathologic myopia

K Ohno-Matsui, PC Wu, K Yamashiro… - … & visual science, 2021 - iovs.arvojournals.org
Pathologic myopia is a major cause of visual impairment worldwide. Pathologic myopia is
distinctly different from high myopia. High myopia is a high degree of myopic refractive error …

[HTML][HTML] IMI–Report on experimental models of emmetropization and myopia

D Troilo, EL Smith, DL Nickla, R Ashby… - … & visual science, 2019 - iovs.arvojournals.org
The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

PG Hysi, H Choquet, AP Khawaja, R Wojciechowski… - Nature …, 2020 - nature.com
Refractive errors, in particular myopia, are a leading cause of morbidity and disability
worldwide. Genetic investigation can improve understanding of the molecular mechanisms …

[HTML][HTML] IMI–myopia genetics report

MS Tedja, AEG Haarman… - … & visual science, 2019 - iovs.arvojournals.org
IMI – Myopia Genetics Report | IOVS | ARVO Journals iovs Issues Topics For Authors About
Editorial Board Journals Home MANAGE ALERTS Access Provided By: Google Indexer Forgot …

[HTML][HTML] The genetic ancestry of african americans, latinos, and european Americans across the United States

K Bryc, EY Durand, JM Macpherson, D Reich… - The American Journal of …, 2015 - cell.com
Over the past 500 years, North America has been the site of ongoing mixing of Native
Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave …

[HTML][HTML] Increasing prevalence of myopia in Europe and the impact of education

KM Williams, G Bertelsen, P Cumberland, C Wolfram… - Ophthalmology, 2015 - Elsevier
Purpose To investigate whether myopia is becoming more common across Europe and
explore whether increasing education levels, an important environmental risk factor for …

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

Education and myopia: assessing the direction of causality by mendelian randomisation

E Mountjoy, NM Davies, D Plotnikov, GD Smith… - bmj, 2018 - bmj.com
Objectives To determine whether more years spent in education is a causal risk factor for
myopia, or whether myopia is a causal risk factor for more years in education. Design …

Control of myopia using diffusion optics spectacle lenses: 12-month results of a randomised controlled, efficacy and safety study (CYPRESS)

J Rappon, C Chung, G Young, C Hunt… - British Journal of …, 2023 - bjo.bmj.com
Background Mutations in the L/M cone opsin gene array cause abnormally high perceived
retinal contrast and the development of myopia. Environmental factors may also lead to high …