Application of platelet-rich plasma in spinal surgery

H Wang, J Zhu, Y Xia, Y Li, C Fu - Frontiers in Endocrinology, 2023 - frontiersin.org
With the aging of the population and changes in lifestyle, the incidence of spine-related
diseases is increasing, which has become a major global public health problem; this results …

Canonical transient receptor potential channels and their modulators: biology, pharmacology and therapeutic potentials

YY Gao, W Tian, HN Zhang, Y Sun, JR Meng… - Archives of Pharmacal …, 2021 - Springer
Canonical transient receptor potential channels (TRPCs) are nonselective, high calcium
permeability cationic channels. The TRPCs family includes TRPC1, TRPC2, TRPC3 …

Microneedle/CD-MOF-mediated transdural controlled release of methylprednisolone sodium succinate after spinal cord injury

X Zhai, K Chen, X Wei, H Zhang, H Yang, K Jiao… - Journal of Controlled …, 2023 - Elsevier
A new method of transdural delivering drugs to the spinal cord has been developed,
involving the use of microneedles (MNs) and a β-cyclodextrin metal-organic framework (CD …

Methylprednisolone induces neuro-protective effects via the inhibition of A1 astrocyte activation in traumatic spinal cord injury mouse models

H Zou, SW Guo, L Zhu, X Xu, J Liu - Frontiers in Neuroscience, 2021 - frontiersin.org
Traumatic spinal cord injury (TSCI) leads to pathological changes such as inflammation,
edema, and neuronal apoptosis. Methylprednisolone (MP) is a glucocorticoid that has a …

Zeolitic imidazole framework-8 loaded gelatin methacryloyl microneedles: A transdural and controlled-release drug delivery system attenuates neuroinflammation …

K Chen, B Li, H Xu, J Wu, J Li, W Sun, M Fang… - International Journal of …, 2024 - Elsevier
Spinal cord injury (SCI) is a matter of significant clinical concern, often treated through early
surgical decompression along with methylprednisolone sodium succinate (MPSS) …

Selective calpain inhibition improves functional and histopathological outcomes in a canine spinal cord injury model

E Metwally, HA Al-Abbadi, MA Hashem… - International Journal of …, 2022 - mdpi.com
Calpain activation has been implicated in various pathologies, including
neurodegeneration. Thus, calpain inhibition could effectively prevent spinal cord injury (SCI) …

The Automatization of the Gait Analysis by the Vicon Video System: A Pilot Study

V Smirnova, R Khamatnurova, N Kharin, E Yaikova… - Sensors, 2022 - mdpi.com
The quality of modern measuring instruments has a strong influence on the speed of
diagnosing diseases of the human musculoskeletal system. The research is focused on …

Methylprednisolone as an adjunct to local infiltration on Laminoplasty or Laminectomy before wound closure: a randomized controlled trial

N Shrestha, B Han, X Wang, W Jia… - Pain Research and …, 2022 - Wiley Online Library
TrialDesign. Patients undergoing laminoplasty and laminectomy often experience severe
postoperative pain. Local infiltration analgesia during spine surgery significantly reduces …

[HTML][HTML] Оценка влияния тяжести травмы спинного мозга на механические свойства костей задних конечностей опытных крыс

АИ Ахметзянова, КР Шарафутдинова… - Российский журнал …, 2022 - cyberleninka.ru
Травмы спинного мозга часто сопровождаются остеопорозом, что осложняет
реабилитацию. При этом влияние тяжести травмы на изменение прочностных свойств …

Administration of methylprednisolone do not affect the spinal scar component of spinal cord injury

X Liu, Y Xu, Y Wang, X Peng, J Jian… - The Journal of Spinal …, 2024 - Taylor & Francis
Objective The aim of this study is to evaluate the impact of methylprednisolone (MP) on scar
composition following spinal cord injury (SCI). Design A total of 40 adult Sprague Dawley …