Achalasia

E Savarino, S Bhatia, S Roman, D Sifrim… - Nature Reviews …, 2022 - nature.com
Achalasia is a rare disorder of the oesophageal smooth muscle characterized by impaired
relaxation of the lower oesophageal sphincter (LES) and absent or spastic contractions in …

Esophageal motility disorders: current approach to diagnostics and therapeutics

DA Patel, R Yadlapati, MF Vaezi - Gastroenterology, 2022 - Elsevier
Dysphagia is a common symptom with significant impact on quality of life. Our diagnostic
armamentarium was primarily limited to endoscopy and barium esophagram until the advent …

Esophagogastric junction outflow obstruction

AJ Bredenoord, A Babaei, D Carlson… - …, 2021 - Wiley Online Library
Abstract In the Chicago Classification version 4.0 (CCv4), esophagogastric junction outflow
obstruction (EGJOO) is manometrically defined as an elevated median integrated relaxation …

The clinical relevance of manometric esophagogastric junction outflow obstruction can be determined using rapid drink challenge and solid swallows

S Sanagapalli, J McGuire, RW Leong… - Official journal of the …, 2021 - journals.lww.com
METHODS: In a retrospective cohort study, we included consecutive subjects between May
2016 and January 2020 with EGJOO. Standard HRM with 5-mL water swallows was …

Diagnosis and management of achalasia: updates of the last two years

A Mari, F Abu Baker, R Pellicano, T Khoury - Journal of Clinical Medicine, 2021 - mdpi.com
Achalasia is a rare neurodegenerative disorder causing dysphagia and is characterized by
abnormal esophageal motor function as well as the loss of lower esophageal sphincter …

Hypercontractile esophagus from pathophysiology to management: proceedings of the Pisa symposium

N de Bortoli, PC Gyawali, S Roman… - Official journal of the …, 2021 - journals.lww.com
Hypercontractile esophagus (HE) is a heterogeneous major motility disorder diagnosed
when≥ 20% hypercontractile peristaltic sequences (distal contractile integral> 8,000 mm …

Esophagogastric junction outflow obstruction: current approach to diagnosis and management

TA Zikos, G Triadafilopoulos, JO Clarke - Current gastroenterology reports, 2020 - Springer
Abstract Purpose of Review We summarize the current epidemiology, presentation,
diagnostic workup, and treatment of esophagogastric junction outflow obstruction (EGJOO) …

How to effectively use and interpret the barium swallow: current role in esophageal dysphagia

S Sanagapalli, A Plumb, RV Lord… - Neurogastroenterology …, 2023 - Wiley Online Library
Background The barium swallow is a commonly performed investigation, though recent
decades have seen major advances in other esophageal diagnostic modalities. Purpose …

Pneumatic dilation improves esophageal emptying and symptoms in patients with idiopathic esophago‐gastric junction outflow obstruction

SB Clayton, CM Shin, A Ewing… - …, 2019 - Wiley Online Library
Abstract Background and aims Idiopathic Esophago‐gastric outflow obstruction (EGJOO) is
a new clinical entity resulting in delayed esophageal emptying secondary to a poorly …

Pharmacologic interrogation of patients with esophagogastric junction outflow obstruction using amyl nitrite

A Babaei, S Shad, A Szabo… - Neurogastroenterology & …, 2019 - Wiley Online Library
Abstract Background The Chicago Classification of esophageal motility includes a group of
patients who show evidence of esophagogastric junction outflow obstruction (EGJOO) as …