Diabetes prevalence continues to climb with the aging population. Type 2 diabetes (T2D),
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …

Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that includes obesity,
diabetes, and dyslipidemia. Accumulating evidence implies that MetS contributes to the …

Type 2 diabetes is a chronic age-associated degenerative metabolic disease that reflects
relative insulin deficiency and resistance. Extracellular vesicles (EVs)(exosomes …

There are currently no disease-modifying therapies for the treatment of tauopathies, a group
of progressive neurodegenerative disorders that are pathologically defined by the presence …

In patients with diabetes, nerve injury is a common complication that leads to chronic pain,
numbness and substantial loss of quality of life. Good glycemic control can decrease the …

A growing body of evidence links type-2 diabetes (T2D) with dementia and
neurodegenerative diseases such as Alzheimer's disease (AD). AD is the most common …

Metabolic syndrome is a cluster of cardiovascular risk factors including obesity, diabetes and
dyslipidemia. Insulin resistance (IR) is at the core of metabolic syndrome. In adipose tissue …

A growing body of clinical and epidemiological research suggests that two of the most
common diseases of aging, type 2 diabetes (T2DM) and Alzheimer disease (AD), are linked …

Insulin is now well-established as playing multiple roles within the brain, and specifically as
regulating hippocampal cognitive processes and metabolism. Impairments to insulin …

Depression and metabolic disorders, including overweight and obesity, appear tightly
interrelated. The prevalence of these conditions is concurrently growing worldwide, and both …