Long non-coding RNA in the pathogenesis of cancers

Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Therapeutic targeting of long non-coding RNAs in cancer

G Arun, SD Diermeier, DL Spector - Trends in molecular medicine, 2018 - cell.com
Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …

[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer

MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …

Long non-coding RNAs in ischemic stroke

MH Bao, V Szeto, BB Yang, S Zhu, HS Sun… - Cell death & …, 2018 - nature.com
Stroke is one of the leading causes of mortality and disability worldwide. Uncovering the
cellular and molecular pathophysiological processes in stroke have been a top priority. Long …

Long noncoding RNA and cancer: a new paradigm

A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

[HTML][HTML] Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease

B Yu, S Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) represent a large subgroup of RNAs that are longer than
200 nucleotides and have no apparent protein coding potential. They have diverse functions …

Lnc RNA‐ATB: An indispensable cancer‐related long noncoding RNA

J Li, Z Li, W Zheng, X Li, Z Wang, Y Cui… - Cell proliferation, 2017 - Wiley Online Library
Abstract Objectives Long non‐coding RNAs (lncRNAs) are a group of non‐protein‐coding
RNA s that are greater than 200 nucleotides in length. Increasing evidence indicates that …

Long non-coding RNAs as the critical regulators of doxorubicin resistance in tumor cells

G Khalili-Tanha, M Moghbeli - Cellular & Molecular Biology Letters, 2021 - Springer
Resistance against conventional chemotherapeutic agents is one of the main reasons for
tumor relapse and poor clinical outcomes in cancer patients. Various mechanisms are …

Exosomal long non-coding RNAs in lung diseases

C Poulet, MS Njock, C Moermans, E Louis… - International journal of …, 2020 - mdpi.com
Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their
secretion within exosomes are a window that could further explain the regulation, the …

Crosstalk between lncRNAs in the apoptotic pathway and therapeutic targets in cancer

N Ebrahimi, S Parkhideh, S Samizade… - Cytokine & growth factor …, 2022 - Elsevier
The assertion that a significant portion of the mammalian genome has not been translated
and that non-coding RNA accounts for over half of polyadenylate RNA have received much …