[HTML][HTML] Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen

Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Harnessing the immune response to fungal pathogens for vaccine development

A Rivera, J Lodge, C Xue - Annual review of microbiology, 2022 - annualreviews.org
Invasive fungal infections are emerging diseases that kill over 1.5 million people per year
worldwide. With the increase of immunocompromised populations, the incidence of invasive …

[HTML][HTML] Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis

JN Jarvis, G Meintjes, T Bicanic, V Buffa… - PLoS …, 2015 - journals.plos.org
Understanding the host immune response during cryptococcal meningitis (CM) is of critical
importance for the development of immunomodulatory therapies. We profiled the …

CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis

LM Neal, E Xing, J Xu, JL Kolbe, JJ Osterholzer… - MBio, 2017 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen that disseminates to the central
nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune …

Mechanisms of cryptococcal virulence and persistence

MA Olszewski, Y Zhang, GB Huffnagle - Future microbiology, 2010 - Taylor & Francis
Cryptococcus neoformans is an environmental yeast that is a leading cause of fatal mycosis
in AIDS patients and a major cause of meningoencephalitis and CNS-related mortality …

[HTML][HTML] Folic acid and vitamins D and B12 correlate with homocysteine in Chinese patients with type-2 diabetes mellitus, hypertension, or cardiovascular disease

X Mao, X Xing, R Xu, Q Gong, Y He, S Li, H Wang… - Medicine, 2016 - journals.lww.com
Folic Acid and Vitamins D and B12 Correlate With Homocystein... : Medicine Folic Acid and
Vitamins D and B12 Correlate With Homocysteine in Chinese Patients With Type-2 Diabetes …

Chemokine levels and chemokine receptor expression in the blood and the cerebrospinal fluid of HIV-infected patients with cryptococcal meningitis and …

CC Chang, S Omarjee, A Lim, T Spelman… - The Journal of …, 2013 - academic.oup.com
Background. Human immunodeficiency virus–infected patients with treated cryptococcal
meningitis who start combination antiretroviral therapy (cART) are at risk of further …

Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity

A Hansakon, P Angkasekwinai - International Immunopharmacology, 2024 - Elsevier
Elevation of arginase enzyme activity in the lung contributes to the pathogenesis of various
chronic inflammatory diseases and infections. Inhibition of arginase expression and activity …

Cryptococcus neoformans and Cryptococcus gattii clinical isolates from Thailand display diverse phenotypic interactions with macrophages

A Hansakon, P Mutthakalin, P Ngamskulrungroj… - Virulence, 2019 - Taylor & Francis
Cryptococcus-macrophage interaction is crucial in the development of cryptococcocal
diseases. C. neoformans and C. gattii are major pathogenic species that occupy different …

Cytomegalovirus viremia associated with increased mortality in cryptococcal meningitis in Sub-Saharan Africa

C Skipper, MR Schleiss, AS Bangdiwala… - Clinical Infectious …, 2020 - academic.oup.com
Background Cryptococcal meningitis and tuberculosis are both important causes of death in
persons with advanced human immunodeficiency virus (HIV)/acquired immunodeficiency …