Supported lipid bilayer coatings: Fabrication, bioconjugation, and diagnostic applications
Supported lipid bilayer (SLB) coatings are versatile, cell-membrane-mimicking biointerfaces
that are useful for fundamental biophysical studies and for various applications such as …
that are useful for fundamental biophysical studies and for various applications such as …
Membrane mimetics for solution NMR studies of membrane proteins
KS Mineev, KD Nadezhdin - Nanotechnology Reviews, 2017 - degruyter.com
Membrane proteins are one of the most challenging and attractive objects in modern
structural biology, as they are targets for the majority of medicines. However, studies of …
structural biology, as they are targets for the majority of medicines. However, studies of …
Mechanisms of membrane protein crystallization in 'bicelles'
TN Murugova, OI Ivankov, YL Ryzhykau, DV Soloviov… - Scientific reports, 2022 - nature.com
Despite remarkable progress, mainly due to the development of LCP and
'bicelle'crystallization, lack of structural information remains a bottleneck in membrane …
'bicelle'crystallization, lack of structural information remains a bottleneck in membrane …
Enhancing the stability and homogeneity of non-ionic polymer nanodiscs by tuning electrostatic interactions
The nanodisc technology is increasingly used for structural studies on membrane proteins
and drug delivery. The development of synthetic polymer nanodiscs and the recent …
and drug delivery. The development of synthetic polymer nanodiscs and the recent …
Change in morphology of dimyristoylphosphatidylcholine/bile salt derivative bicelle assemblies with dodecylmaltoside in the disk and ribbon phases
Bicelles, composed of a mixture of long and short chain lipids, form nanostructured
molecular assemblies that are attractive lipid-membrane mimics for in vitro studies of integral …
molecular assemblies that are attractive lipid-membrane mimics for in vitro studies of integral …
Characterization of small isotropic bicelles with various compositions
Structural studies of membrane proteins are of great importance and interest, with solution
and solid state NMR spectroscopy being very promising tools for that task. However, such …
and solid state NMR spectroscopy being very promising tools for that task. However, such …
Interaction of the saponin aescin with ibuprofen in DMPC model membranes
In the present work, we study the interaction of the saponin aescin with the nonsteroidal anti-
inflammatory drug (NSAID) ibuprofen at concentrations of 1.2–2.5 mM. These amounts are …
inflammatory drug (NSAID) ibuprofen at concentrations of 1.2–2.5 mM. These amounts are …
Lipid environment modulates processivity and kinetics of a presenilin homolog acting on multiple substrates in vitro
Intramembrane proteases (IPs) hydrolyze peptides in the lipid membrane. IPs participate in
a number of cellular pathways including immune response and surveillance, and cholesterol …
a number of cellular pathways including immune response and surveillance, and cholesterol …
Morphological control and modern applications of bicelles
J Amengual, L Notaro-Roberts, MP Nieh - Biophysical Chemistry, 2023 - Elsevier
Bicellar systems have become popularized as their rich morphology can be applied in
biochemistry, physical chemistry, and drug delivery technology. To the biochemical field …
biochemistry, physical chemistry, and drug delivery technology. To the biochemical field …
Supported lipid bilayer formation from phospholipid-fatty acid bicellar mixtures
Supported lipid bilayers (SLBs) are versatile cell membrane-mimicking biointerfaces for
various applications such as biosensors and drug delivery systems, and there is broad …
various applications such as biosensors and drug delivery systems, and there is broad …