[HTML][HTML] A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine

S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …

[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model

AS Cone, X Yuan, L Sun, LC Duke, MP Vreones… - Theranostics, 2021 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …

[HTML][HTML] BMSC-derived exosomal miR-29a promotes angiogenesis and osteogenesis

G Lu, P Cheng, T Liu, Z Wang - Frontiers in cell and developmental …, 2020 - frontiersin.org
Angiogenesis and osteogenesis are tightly coupled during bone modeling and remodeling
processes. Here we reported that bone marrow mesenchymal stem cell (BMSC)-derived …

[HTML][HTML] Clinical utility of mesenchymal stem/stromal cells in regenerative medicine and cellular therapy

VV Maldonado, NH Patel, EE Smith, CL Barnes… - Journal of biological …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous
potential in regenerative medicine. With their immunomodulatory and regenerative …

[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease

T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …

[HTML][HTML] The emerging role of neural cell-derived exosomes in intercellular communication in health and neurodegenerative diseases

L Huo, X Du, X Li, S Liu, Y Xu - Frontiers in Neuroscience, 2021 - frontiersin.org
Intercellular communication in the central nervous system (CNS) is essential for brain
growth, development, and homeostasis maintenance and, when dysfunctional, is involved in …

[HTML][HTML] The potential use of mesenchymal stem cells and their derived exosomes for orthopedic diseases treatment

K Malekpour, A Hazrati, M Zahar, A Markov… - Stem cell reviews and …, 2022 - Springer
Musculoskeletal disorders (MSDs) are conditions that can affect muscles, bones, and joints.
These disorders are very painful and severely limit patients' mobility and are more common …

[HTML][HTML] Extracellular vesicles, from the pathogenesis to the therapy of neurodegenerative diseases

X Xia, Y Wang, JC Zheng - Translational Neurodegeneration, 2022 - Springer
Extracellular vesicles (EVs) are small bilipid layer-enclosed vesicles that can be secreted by
all tested types of brain cells. Being a key intercellular communicator, EVs have emerged as …

Insulin-producing cells from bone marrow stem cells versus injectable insulin for the treatment of rats with type I diabetes

SH Azeez, SN Jafar, Z Aziziaram, L Fang… - Cellular, Molecular …, 2021 - cmbr-journal.com
Recently, stem cells have been considered renewable cell sources in the treatment of
diabetes and the development of insulin-producing cells. In this regard, the current study …